Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329869 | 0.92 | ESR1 (0.42) | ESR1SIRT2IDH1KIF11 | |
| SCHEMBL29330563 | 0.88 | PRKCQ (0.39) | ESR1SIRT2PRKCQMETSLC2A1 | |
| SCHEMBL29329290 | 0.87 | PRKCQ (0.42) | ESR1PRKCQMET | |
| SCHEMBL29328815 | 0.87 | MAOB (0.40) | SIRT2PRKCQMET | |
| SCHEMBL29329720 | 0.85 | TTBK1 (0.46) | ESR1PRKCQIDH1KIF11TTBK1 | |
| SCHEMBL29329365 | 0.85 | MET (0.40) | ESR1PRKCQMET | |
| SCHEMBL29330428 | 0.84 | ESR1 (0.42) | ESR1PRKCQGALR2 | |
| SCHEMBL29329726 | 0.84 | SYK (0.39) | ESR1PRKCQMET | |
| SCHEMBL29330026 | 0.83 | SIRT2 (0.40) | ESR1SIRT2PRKCQ | |
| SCHEMBL29329867 | 0.82 | PRKCQ (0.40) | ESR1SIRT2PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |