Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.36 |
| ▸ | MYLK | Q15746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592917 | 0.84 | PRKCE (0.35) | ALDH1A1PRKCEMYLKTDP1MEN1 | |
| SCHEMBL16592864 | 0.79 | GABRA1 (0.35) | ALDH1A1PRKCEMYLKTDP1MEN1 | |
| SCHEMBL16592890 | 0.79 | GABRA1 (0.37) | ALDH1A1PRKCEMYLKTDP1MEN1 | |
| SCHEMBL16592937 | 0.77 | PRKCE (0.42) | ALDH1A1PRKCEMYLKTDP1MEN1 | |
| SCHEMBL28569210 | 0.77 | TDP1 (0.41) | ALDH1A1PRKCEMYLKTDP1MEN1 | |
| SCHEMBL26137718 | 0.75 | TRPA1 (0.47) | ALDH1A1TDP1LMNAKDM4E | |
| SCHEMBL24469036 | 0.74 | SHBG (0.33) | ALDH1A1LMNA | |
| SCHEMBL2115983 | 0.74 | ALDH1A1 (0.52) | ALDH1A1PRKCEMYLKTDP1MEN1 | |
| SCHEMBL10582835 | 0.74 | ACHE (0.46) | ALDH1A1PRKCEMYLKTDP1MEN1 | |
| SCHEMBL13696445 | 0.73 | ALDH1A1 (0.36) | ALDH1A1PRKCEMYLKTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |