SCHEMBL2933377

SCHEMBL2933377

C=CC(=O)Oc1ccccc1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.49
THRA P10827 1/20 0.49
ALDH1A1 P00352 4/20 0.43
KMT2A Q03164 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
FAAH O00519 3/20 0.43
MAPT P10636 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HPGD P15428 3/20 0.42
KDM4E B2RXH2 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PARP10 Q53GL7 1/20 0.41
CXCL8 P10145 1/20 0.41
TYMS P04818 1/20 0.40
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
GAA P10253 1/20 0.39
LMNA P02545 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30596839 1.00 THRB (0.49) THRBTHRAALDH1A1KMT2AL3MBTL1
Hydrochloric Acid SCHEMBL28527576 0.98 THRB (0.48) THRBTHRAALDH1A1KMT2AL3MBTL1
SCHEMBL3841280 0.86 THRB (0.56) THRBTHRAALDH1A1KMT2AMAPT
SCHEMBL29413361 0.86 THRB (0.56) THRBTHRAALDH1A1KMT2AMAPT
SCHEMBL10180879 0.85 THRB (0.43) THRBTHRAALDH1A1KMT2AL3MBTL1
SCHEMBL28538498 0.83 MAOA (0.46) ALDH1A1LMNA
SCHEMBL5066071 0.82 ALDH1A1 (0.47) ALDH1A1KMT2AL3MBTL1FAAHMAPT
SCHEMBL3952990 0.82 FAAH (0.46) THRBTHRAALDH1A1KMT2AL3MBTL1
SCHEMBL10180753 0.81 CES2 (0.41) THRBTHRAKMT2AMAPTTYMS
SCHEMBL9790241 0.81 ALDH1A1 (0.41) THRBTHRAALDH1A1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447921-B High refractive index optical organic glue composition and preparation method thereof 东莞市诺尔斯有机硅科技有限公司 2024-05-21 CN claimed
CN-112898276-A Chalcone derivative and application thereof 深圳市第二人民医院(深圳市转化医学研究院) 2021-06-04 CN claimed
EP-0095932-B1 THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-08-06 EP claimed
EP-0095932-A1 The use of a particulate polymer as a carrier for biological substances and the like and such substances supported on the carrier JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-12-07 EP claimed
CN-115710248-B Novel selective estrogen receptor down-regulator compound, preparation method and application 南京中医药大学 2024-06-21 CN disclosed
CN-117447921-B High refractive index optical organic glue composition and preparation method thereof 东莞市诺尔斯有机硅科技有限公司 2024-05-21 CN disclosed
CN-117820287-A Magnolol derivative, and preparation method and application thereof 中国药科大学 2024-04-05 CN disclosed
CN-117402123-A Alpha, beta-unsaturated amide compounds, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2024-01-16 CN disclosed
CN-116768792-A Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof 浙江工业大学 2023-09-19 CN disclosed
CN-112204018-B Acrylic compound, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2023-08-29 CN disclosed
CN-115710248-A Novel selective estrogen receptor down-regulator compounds, methods of preparation and uses 南京中医药大学 2023-02-24 CN disclosed
US-11472891-B2 Photocrosslinkable alginic acid derivative MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-10-18 US disclosed
US-5389708-A Polymerizing polyisocyanate or polyisothiocyanate with polyol or polythiol in presence of thiophosphoric or dithiophosphoric acid ester MITSUI TOATSU CHEMICALS, INC. (JP) 1995-02-14 US disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5155190-A Suspension polymerization, excellent heat resistance, weatherproofing and transparency HITACHI CHEMICAL COMPANY (JP) 1992-10-13 US disclosed
US-RE34061-E And one or more unsaturated monomes; transparency, heat and moisture resistance optical elements HITACHI CHEMICAL CO., LTD. (JP) 1992-09-08 US disclosed
EP-0095932-B1 THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-08-06 EP disclosed
US-4591626-A TRANSPARENT OPTICAL MATERIALS HITACHI CHEMICAL COMPANY, LTD. (JP) 1986-05-27 US disclosed
EP-0141610-A2 Optical elements comprising polymers of (meth)acrylate esters Hitachi Chemical Co., Ltd. (JP) 1985-05-15 EP disclosed
EP-0095932-A1 The use of a particulate polymer as a carrier for biological substances and the like and such substances supported on the carrier JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-12-07 EP disclosed