Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387492 | 0.79 | ASPH (0.46) | ASPHNOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL30483541 | 0.78 | EPRS1 (0.46) | ASPHNOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL24566862 | 0.78 | KDM4E (0.43) | ASPHNOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL25111974 | 0.78 | EPRS1 (0.46) | ASPHNOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL8389880 | 0.78 | ASPH (0.42) | ASPHNOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL257449 | 0.77 | CES2 (0.48) | ASPHNOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL27218352 | 0.74 | XDH (0.45) | ASPHTAS2R14 | |
| SCHEMBL3036944 | 0.71 | ASPH (0.59) | ASPHNOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL15920412 | 0.71 | ASPH (0.53) | ASPHNOTUMALDH1A1KDM4EHPGD | |
| SCHEMBL398909 | 0.69 | KAT6A (0.54) | NOTUMALDH1A1KDM4EHPGDTAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400497-A1 | 3CLPRO PROTEASE INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2024-07-17 | — | — | EP | disclosed |