Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29339015 | 0.74 | BTK (0.38) | MAPK1 | |
| SCHEMBL29338952 | 0.74 | BTK (0.37) | MAPK1 | |
| SCHEMBL29341894 | 0.73 | MAPK1 (0.63) | MAPK1MAPK3 | |
| SCHEMBL18794310 | 0.72 | MAPK1 (0.65) | MAPK1MAPK3 | |
| SCHEMBL29343703 | 0.72 | MAPK1 (0.61) | MAPK1MAPK3 | |
| SCHEMBL29344797 | 0.71 | MAPK1 (0.62) | MAPK1MAPK3 | |
| SCHEMBL18794084 | 0.71 | HIF1A (0.39) | MAPK1 | |
| SCHEMBL29339151 | 0.70 | SMN1; SMN2 (0.52) | MAPK1 | |
| SCHEMBL29340146 | 0.70 | BTK (0.36) | — | |
| SCHEMBL29339043 | 0.67 | MAPK1 (0.52) | MAPK1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |