SCHEMBL29339219

SCHEMBL29339219

O=C1c2cc(Br)oc2C(=O)c2cc(Br)oc21

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 4/20 0.38
ALDH1A1 P00352 1/20 0.38
S100A4 P26447 1/20 0.32
GPR35 Q9HC97 1/20 0.31
NQO1 P15559 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
RECQL P46063 1/20 0.31
MCL1 Q07820 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28705 0.87 STAT3 (0.56) STAT3ALDH1A1S100A4POLBMAPT
SCHEMBL6577994 0.64 STAT3 (0.61) STAT3ALDH1A1S100A4POLBMAPT
SCHEMBL11928939 0.63 NQO1 (0.48) STAT3ALDH1A1NQO1POLBMAPT
SCHEMBL1901529 0.53
SCHEMBL3861575 0.53 S100A4 (0.32) S100A4
SCHEMBL14199249 0.50
SCHEMBL855808 0.50 ALOX15 (0.48) ALDH1A1TDP1
SCHEMBL1569445 0.48
SCHEMBL31025596 0.45 GPR35 (0.34) ALDH1A1GPR35NQO1POLBHPGD
SCHEMBL15763 0.45 CYP1A2 (0.43) ALDH1A1GPR35NQO1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 US disclosed
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device TRMT1L, TLK1, TSPO STAT3 4059/4885ALDH1A1 1272/4885S100A4 2396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.