SCHEMBL2934101

SCHEMBL2934101

C[Si](C)(C)C#Cc1cccc(C=O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.46
ALDH1A1 P00352 4/20 0.41
BRD4 O60885 1/20 0.40
UNG P13051 1/20 0.38
CYP2A6 P11509 1/20 0.35
TSHR P16473 1/20 0.35
SRC P12931 1/20 0.34
MAOA P21397 3/20 0.33
MAOB P27338 3/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
POLB P06746 1/20 0.33
FGFR1 P11362 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31044602 1.00 FFAR1 (0.46) FFAR1ALDH1A1BRD4UNGCYP2A6
SCHEMBL10633500 0.82 FFAR1 (0.58) FFAR1ALDH1A1BRD4UNGCYP2A6
SCHEMBL24835098 0.81 LOX (0.32)
SCHEMBL31574360 0.81 LOX (0.32)
SCHEMBL3614755 0.80 GRM5 (0.39) ALDH1A1GABRA1GABRG2GABRB3GABRA5
SCHEMBL9699028 0.79 FFAR1 (0.49) FFAR1ALDH1A1BRD4UNGCYP2A6
SCHEMBL3735218 0.77 FFAR1 (0.62) FFAR1ALDH1A1UNGCYP2A6MAOA
SCHEMBL701214 0.77 CYP2A6 (0.43) ALDH1A1BRD4CYP2A6GABRA1GABRG2
SCHEMBL29622470 0.77 FFAR1 (0.62) FFAR1ALDH1A1UNGCYP2A6MAOA
SCHEMBL30409291 0.75 GRM5 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260093180-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE AND COMPOSITION FOR FILM FORMATION JSR CORPORATION (JP) 2026-04-02 US disclosed
WO-2024034311-A1 SEMICONDUCTOR SUBSTRATE PRODUCTION METHOD AND FILM FORMING COMPOSITION JSR株式会社 2024-02-15 WO disclosed
US-11814462-B2 Functionalized cyclic polymers and methods of preparing same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-14 US disclosed
US-20220056167-A1 Functionalized Cyclic Polymers and Methods of Preparing Same NATIONAL SCIENCE FOUNDATION 2022-02-24 US disclosed
WO-2020223672-A1 FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) 2020-11-05 WO disclosed
CN-111285874-A RET inhibitors, pharmaceutical compositions thereof and uses thereof 广东东阳光药业有限公司 2020-06-16 CN disclosed
US-20100279936-A1 SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES LEO PHARMA A/S (DK) 2010-11-04 US disclosed
EP-2229377-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS Wyeth LLC (US) 2010-09-22 EP disclosed
WO-2010063487-A1 PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE MERZ PHARMA GMBH & CO. KGAA (DE) 2010-06-10 WO disclosed
WO-2009076602-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS WYETH (US) 2009-06-18 WO disclosed
US-7067653-B2 Porphyrin Based neuton capture agents for cancer therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-06-27 US disclosed
US-20040116385-A1 Treating and preventing viral infections with porphyrin-based compounds BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2004-06-17 US disclosed
US-20040106592-A1 Chelation of charged and uncharged molecules with porphyrin-based compounds BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2004-06-03 US disclosed
US-20040014737-A1 Porphyron based neuton capture agents for cancer therapy REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2004-01-22 US disclosed
WO-2001085736-A1 PORPHYRIN-BASED NEUTRON CAPTURE AGENTS FOR CANCER THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-11-15 WO disclosed
US-5321165-A Synthetic method for ethynylation of aromatic compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1994-06-14 US disclosed
US-4587315-A Diethynylated phenylbenzimidazole compounds HUGHES AIRCRAFT COMPANY (US) 1986-05-06 US disclosed
US-4537974-A Diethynylated phenylbenzimidazole compounds HUGHES AIRCRAFT COMPANY (US) 1985-08-27 US disclosed
US-4465833-A ALKYNYLATION HALOGENATED BENZENE COMPOUND IN PRESENCE OF METAL CATALYST HUGHES AIRCRAFT COMPANY (US) 1984-08-14 US disclosed
EP-0050428-A1 Ethynylated aromatic compounds and process for making same Hughes Aircraft Company (US) 1982-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260093180-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE AND COMPOSITION FOR FILM FORMATION SMC4, TYR, SMC2 FFAR1 3731/4885ALDH1A1 2634/4885BRD4 2937/4885
US-20100279936-A1 SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES C1R, C3AR1, PTH1R FFAR1 232/4885ALDH1A1 1976/4885BRD4 2538/4885
US-20040106592-A1 Chelation of charged and uncharged molecules with porphyrin-based compounds HMBS, PPOX, SLC7A1 FFAR1 2275/4885ALDH1A1 4749/4885BRD4 1809/4885
US-20040014737-A1 Porphyron based neuton capture agents for cancer therapy PPOX, HMBS, PYGB FFAR1 4490/4885ALDH1A1 4029/4885BRD4 1761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.