Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | HRAS | P01112 | 1/20 | 0.30 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344749 | 0.89 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL23351255 | 0.89 | ALDH1A1 (0.32) | CRHR1HRASKRASP2RX7 | |
| SCHEMBL29344717 | 0.87 | CDK2 (0.33) | CRHR1HRASKRAS | |
| SCHEMBL29344684 | 0.85 | POLB (0.30) | — | |
| SCHEMBL26993043 | 0.81 | TYK2 (0.38) | — | |
| SCHEMBL29344871 | 0.80 | PTPN1 (0.34) | P2RX7 | |
| SCHEMBL29344732 | 0.79 | P2RX7 (0.31) | CRHR1P2RX7 | |
| SCHEMBL29344739 | 0.79 | CXCR3 (0.33) | P2RX7 | |
| SCHEMBL29344741 | 0.79 | CXCR3 (0.32) | P2RX7 | |
| SCHEMBL29344691 | 0.78 | TYK2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |