Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.33 |
| ▸ | ACVR1B | P36896 | 4/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.33 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | CCNH | P51946 | 2/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | HRAS | P01112 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344684 | 0.93 | POLB (0.30) | POLB | |
| SCHEMBL29344739 | 0.91 | CXCR3 (0.33) | CDK2CCNE1CDK9 | |
| SCHEMBL23351255 | 0.89 | ALDH1A1 (0.32) | HRASKRASCRHR1 | |
| SCHEMBL29344747 | 0.89 | P2RX7 (0.30) | CDK2 | |
| SCHEMBL29344696 | 0.87 | CRHR1 (0.33) | HRASKRASCRHR1 | |
| SCHEMBL29344741 | 0.85 | CXCR3 (0.32) | — | |
| SCHEMBL29344736 | 0.84 | CXCR3 (0.32) | — | |
| SCHEMBL29344732 | 0.84 | P2RX7 (0.31) | CRHR1 | |
| SCHEMBL29344724 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL29344744 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |