Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23351255 | 0.91 | ALDH1A1 (0.32) | P2RX7ALDH1A1KMT2A | |
| SCHEMBL29344739 | 0.90 | CXCR3 (0.33) | GPBAR1P2RX7ALDH1A1CXCR3LMNA | |
| SCHEMBL29344741 | 0.88 | CXCR3 (0.32) | GPBAR1P2RX7ALDH1A1CXCR3LMNA | |
| SCHEMBL29344736 | 0.87 | CXCR3 (0.32) | PTPN1GPBAR1P2RX7ALDH1A1CXCR3 | |
| SCHEMBL29344747 | 0.81 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL29344749 | 0.81 | P2RX7 (0.33) | P2RX7ERBB2EPHA2EPHB4 | |
| SCHEMBL29344717 | 0.81 | CDK2 (0.33) | POLB | |
| SCHEMBL29344696 | 0.80 | CRHR1 (0.33) | P2RX7 | |
| SCHEMBL29344744 | 0.79 | — | — | |
| SCHEMBL26253809 | 0.79 | MAPT (0.34) | ALDH1A1MAPTPOLBLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |