Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | BLK | P51451 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24367126 | 0.87 | ALDH1A1 (0.55) | ALDH1A1BTKTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL24367131 | 0.67 | GPR35 (0.41) | TSHRRAB9AMAPT | |
| SCHEMBL31430203 | 0.67 | MAPT (0.51) | ALDH1A1RAB9AMAPTGAAGRM4 | |
| SCHEMBL31430313 | 0.67 | MAPT (0.51) | ALDH1A1RAB9AMAPTGAAGRM4 | |
| SCHEMBL22625559 | 0.67 | RAF1 (0.43) | ALDH1A1BTKTSHRBLKRAB9A | |
| SCHEMBL20143373 | 0.66 | ALDH1A1 (0.62) | ALDH1A1RAB9AKMT2AMAPTGAA | |
| SCHEMBL22652926 | 0.66 | ALDH1A1 (0.42) | ALDH1A1BTKTSHRBLKRAB9A | |
| SCHEMBL8705485 | 0.65 | RAB9A (0.53) | ALDH1A1MAPKAPK2RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL29739561 | 0.65 | RAB9A (0.53) | ALDH1A1MAPKAPK2RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL24879177 | 0.64 | WNT3A (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228478-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | ALDH1A1 128/4885MAPKAPK2 4853/4885MAP4K1 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.