SCHEMBL29349497

SCHEMBL29349497

N[C@@H](Cc1c[nH]cn1)C(=O)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ ABL1 P00519 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ PKM P14618 1/20 0.53
▸ IDE P14735 1/20 0.53
▸ MAPK1 P28482 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ RIN1 Q13671 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ CA12 O43570 10/20 0.47
▸ CA1 P00915 10/20 0.47
▸ CA2 P00918 10/20 0.47
▸ CA9 Q16790 10/20 0.47
▸ HLCS P50747 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL20495575 0.89 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL6734256 0.89 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
SCHEMBL30081014 0.83 TDP1 (0.53) TDP1MEN1ABL1LMNAPKM
SCHEMBL30058455 0.82 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM
SCHEMBL24220337 0.81 TDP1 (0.55) TDP1PKMCA12CA1CA2
Biotin SCHEMBL10612975 0.80 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM
Histidine SCHEMBL2269187 0.79 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
SCHEMBL31364275 0.78 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
SCHEMBL29462121 0.78 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
SCHEMBL29460474 0.77 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026103797-A1 ANTI-B7H4 SINGLE-DOMAIN ANTIBODY AND USE THEREOF 博生吉医药科技(苏州)有限公司 2026-05-21 — — WO disclosed
EP-4744731-A2 ANTI-HUMAN P40 PROTEIN DOMAIN ANTIBODY AND USE THEREOF Akeso Biopharma, Inc. (CN) 2026-05-20 — — EP disclosed
CN-122036946-A Anti-B7H 4 single domain antibody and application thereof 博生吉医药科技(苏州)有限公司 2026-05-15 — — CN disclosed
EP-4739716-A1 EGFR/C-MET BISPECIFIC BINDING PROTEIN AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2026-05-13 — — EP disclosed
EP-4739715-A1 EGFR/C-MET BISPECIFIC BINDING PROTEIN AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2026-05-13 — — EP disclosed
US-20260116972-A1 CROSS-SPECIES-SPECIFIC PSCAXCD3, CD19XCD3, C-METXCD3, ENDOSIALINXCD3, EPCAMXCD3, IGF-1RXCD3 OR FAPALPHAXCD3 BISPECIFIC SINGLE CHAIN ANTIBODY AMGEN RES MUNICH GMBH (DE) 2026-04-30 — — US disclosed
EP-4725500-A2 ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF Merck Patent GmbH (DE) 2026-04-15 — — EP disclosed
US-12595300-B2 Anti-human P40 protein domain antibody and use thereof AKESO BIOPHARMA, INC. (CN) 2026-04-07 — — US disclosed
US-20260092115-A1 FC VARIANTS CHUGAI PHARMACEUTICAL CO LTD (JP) 2026-04-02 — — US disclosed
EP-4208481-B1 ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF MERCK PATENT GMBH (DE) 2026-03-04 — — EP disclosed
CN-114366746-A Treatment of cancer using oxoisoindole compounds 细胞基因公司 2022-04-19 — — CN disclosed
CN-114344307-A Treatment of cancer using oxoisoindole compounds 细胞基因公司 2022-04-15 — — CN disclosed
CN-114286827-A Humanized anti-IL 17A antibodies and uses thereof 神州细胞工程有限公司 2022-04-05 — — CN disclosed
WO-2022058618-A2 SARS-COV2 ANTIBODIES IONTAS LIMITED (GB) 2022-03-24 — — WO disclosed
WO-2022048883-A1 ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF MERCK PATENT GMBH (DE) 2022-03-10 — — WO disclosed
CN-114057877-A anti-PD-L1 antibody and application thereof 百奥泰生物制药股份有限公司 2022-02-18 — — CN disclosed
EP-3954709-A1 BISPECIFIC ANTIBODIES SPECIFIC FOR PD1 AND TIM3 F. Hoffmann-La Roche AG (CH) 2022-02-16 — — EP disclosed
WO-2022028608-A1 ANTI PD-L1 ANTIBODY AND APPLICATION THEREOF 百奥泰生物制药股份有限公司 2022-02-10 — — WO disclosed
US-20220041736-A1 CROSS-SPECIES-SPECIFIC SINGLE DOMAIN BISPECIFIC SINGLE CHAIN ANTIBODY AMGEN RESEARCH (MUNICH) GMBH (DE) 2022-02-10 — — US disclosed
CN-107206072-B Combination therapy of the T cell activating bispecific antigen binding molecule CD3 ABD folate receptor 1(FolR1) and a PD-1 axis binding antagonist 豪夫迈·罗氏有限公司 2022-01-21 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595300-B2 Anti-human P40 protein domain antibody and use thereof FCGRT, FCGR3B, VSIG8 TDP1 1471/4885MEN1 2957/4885ABL1 3243/4885
US-20260092115-A1 FC VARIANTS FCGR3B, FCGR2A, FCGR1A TDP1 184/4885MEN1 3186/4885ABL1 287/4885
US-20260116972-A1 CROSS-SPECIES-SPECIFIC PSCAXCD3, CD19XCD3, C-METXCD3, ENDOSIALINXCD3, EPCAMXCD3, IGF-1RXCD3 OR FAPALPHAXCD3 BISPECIFIC SINGLE CHAIN ANTIBODY MET, IGF1R, INHA TDP1 3260/4885MEN1 217/4885ABL1 823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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