Talastine

Talastine

SCHEMBL29350005

CN(C)CCn1nc(Cc2ccccc2)c2ccccc2c1=O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 9/20 0.81
HRH1 P35367 9/20 0.81
ADRA1B P35368 9/20 0.81
HRH3 Q9Y5N1 4/20 0.70
TSHR P16473 1/20 0.63
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
GLA P06280 1/20 0.55
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
KCNH2 Q12809 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Talastine SCHEMBL30502 1.00 ADRA1A (0.81) ADRA1AHRH1ADRA1BHRH3TSHR
Talastine SCHEMBL1650995 0.97 ADRA1A (0.78) ADRA1AHRH1ADRA1BHRH3TSHR
Talastine SCHEMBL13724065 0.83 HRH1 (0.58) ADRA1AHRH1ADRA1BHRH3TSHR
SCHEMBL10482471 0.82 ADRA1A (0.61) ADRA1AHRH1ADRA1BHRH3TSHR
SCHEMBL16363659 0.82 TSHR (0.64) ADRA1AHRH1ADRA1BHRH3TSHR
SCHEMBL12877772 0.81 TSHR (0.71) ADRA1AHRH1ADRA1BHRH3TSHR
Talastine SCHEMBL28086448 0.80 HRH1 (0.60) ADRA1AHRH1ADRA1BHRH3TSHR
SCHEMBL10700249 0.79 ADRA1A (0.57) ADRA1AHRH1ADRA1BHRH3TSHR
SCHEMBL8556390 0.78 ENPP1 (0.65) ADRA1AHRH1ADRA1BTSHRCYP1A2
SCHEMBL12862542 0.78 TSHR (0.66) ADRA1AHRH1ADRA1BHRH3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041208-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2025-02-06 US claimed
EP-4444277-A1 NEW INJECTABLE COMBINATION FORMULATION Nanexa AB (SE) 2024-10-16 EP claimed
WO-2023105227-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2023-06-15 WO claimed
EP-4633602-A1 NEW PHARMACEUTICAL COMPOSITIONS COMPRISING GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONISTS Nanexa AB (SE) 2025-10-22 EP disclosed
US-20250312275-A1 GAS PHASE DEPOSITION TECHNIQUE FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS NANEXA AB (SE) 2025-10-09 US disclosed
EP-4536179-A1 GAS PHASE DEPOSITION TECHNIQUE FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS Nanexa AB (SE) 2025-04-16 EP disclosed
US-20250073219-A1 NEW COMPOSITION COMPRISING IMMUNOMODULATORY DRUG NANEXA AB (SE) 2025-03-06 US disclosed
US-20250041208-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2025-02-06 US disclosed
WO-2024256696-A1 NEW INJECTABLE PHARMACEUTICAL DEPOT COMPOSITIONS NANEXA AB (SE) 2024-12-19 WO disclosed
EP-4444277-A1 NEW INJECTABLE COMBINATION FORMULATION Nanexa AB (SE) 2024-10-16 EP disclosed
US-20240277749-A1 NEW FORMULATIONS COMPRISING AZACITIDINE NANEXA AB (SE) 2024-08-22 US disclosed
EP-4351529-A1 NEW FORMULATIONS COMPRISING BIOLOGIC ACTIVE DRUGS Nanexa AB (SE) 2024-04-17 EP disclosed
WO-2023237897-A1 GAS PHASE DEPOSITION TECHNIQUE FOR PREPARATION OF PHARMACEUTICAL COMPOSITIONS NANEXA AB (SE) 2023-12-14 WO disclosed
CN-111971067-B Tannic acid-containing heart targeting agent 韩国化学研究院 2023-09-08 CN disclosed
WO-2023105227-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2023-06-15 WO disclosed
WO-2022258988-A1 NEW COMPOSITION COMPRISING IMMUNOMODULATORY DRUG NANEXA AB (SE) 2022-12-15 WO disclosed
WO-2022258987-A1 NEW FORMULATIONS COMPRISING AZACITIDINE NANEXA AB (SE) 2022-12-15 WO disclosed
WO-2022258985-A1 NEW FORMULATIONS COMPRISING BIOLOGIC ACTIVE DRUGS NANEXA AB (SE) 2022-12-15 WO disclosed
US-11446384-B2 Agent for targeting heart comprising tannic acid KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2022-09-20 US disclosed
CN-113115799-B Application of turmeric volatile oil 沈阳恩柽研究院有限公司 2022-01-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11446384-B2 Agent for targeting heart comprising tannic acid TNNT2, TNNI3, TNNC1 ADRA1A 893/4885HRH1 2274/4885ADRA1B 2052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.