SCHEMBL29351470

SCHEMBL29351470

Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4cccnc4)cc3)cc2)ccn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PORCN Q9H237 2/20 1.00
WNT3A P56704 15/20 0.81
PSEN1 P49768 2/20 0.67
PSEN2 P49810 2/20 0.67
APH1B Q8WW43 2/20 0.67
NCSTN Q92542 2/20 0.67
APH1A Q96BI3 2/20 0.67
PSENEN Q9NZ42 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1724609 1.00 PORCN (1.00) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL1723593 0.90 WNT3A (1.00) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL2182327 0.90 WNT3A (1.00) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL1723832 0.89 WNT3A (1.00) PORCNWNT3A
SCHEMBL2454059 0.86 WNT3A (1.00) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL27971532 0.86 WNT3A (0.93) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL2182842 0.86 WNT3A (0.93) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL2184335 0.84 WNT3A (0.80) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL2184404 0.84 WNT3A (0.80) PORCNWNT3APSEN1PSEN2APH1B
SCHEMBL1492885 0.83 PORCN (0.71) PORCNWNT3APSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 723 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122038285-A Kit and method for constructing human bone organ by using pluripotent stem cells 广东医科大学附属医院 2026-05-15 CN claimed
EP-4728051-A1 STANDARDISING PLURIPOTENT STEM CELLS United Kingdom Research and Innovation (GB) 2026-04-22 EP claimed
US-12570956-B2 Efficient derivation of stable pluripotent bovine embryonic stem cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-10 US claimed
US-20260022347-A1 TREATMENT AGENT FOR LUNG ADENOCARCINOMAS UNIV KEIO (JP) 2026-01-22 US claimed
EP-4346928-B1 BIODEGRADABLE TISSUE SCAFFOLD WITH SECONDARY MATRIX TO HOST WEAKLY ADHERENT CELLS US HEALTH (US) 2026-01-14 EP claimed
US-20260002121-A1 IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES CHILDRENS HOSPITAL MED CT (US) 2026-01-01 US claimed
WO-2025262235-A1 UNGULATE PLURIPOTENT STEM CELL CULTURE MEDIUM MEAT TOMORROW APS (DK) 2025-12-26 WO claimed
US-12503685-B2 Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2025-12-23 US claimed
US-12485147-B2 Method for producing cell mass including pituitary tissue, and cell mass thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-12-02 US claimed
US-12486495-B2 Cardiac organoid, manufacturing method therefor, and method for evaluating drug toxicity by using same INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2025-12-02 US claimed
CN-114438037-A Method for preparing inductive mesenchymal stem cells 深圳市乐土生物医药有限公司 2022-05-06 CN claimed
WO-2022051847-A9 METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY UNIVERSITY HEALTH NETWORK (CA) 2022-04-21 WO claimed
CN-114369577-A Cattle induced expansion pluripotent adult stem cell, line establishing method and culture solution 内蒙古大学 2022-04-19 CN claimed
CN-114369567-A Method for establishing bovine expanded pluripotent embryonic stem cells and culture solution 内蒙古大学 2022-04-19 CN claimed
WO-2022031952-A9 TREATMENTS FOR CANCERS HAVING KRAS MUTATIONS CITY OF HOPE (US) 2022-04-07 WO claimed
WO-2022063224-A1 ACTIVATED PLURIPOTENT STEM CELL, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国科学院动物研究所 2022-03-31 WO claimed
CN-114250195-A Activated pluripotent stem cell and preparation method and application thereof 中国科学院动物研究所 2022-03-29 CN claimed
WO-2022051847-A1 METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY UNIVERSITY HEALTH NETWORK (CA) 2022-03-17 WO claimed
WO-2022031952-A2 TREATMENTS FOR CANCERS HAVING KRAS MUTATIONS CITY OF HOPE (US) 2022-02-10 WO claimed
WO-2022020967-A1 USE OF WNT/BETA-CATENIN PATHWAY INHIBITORS TO BLOCK REPLICATION OF SARS-COV-2 AND OTHER PATHOGENIC VIRUSES THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2022-02-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022347-A1 TREATMENT AGENT FOR LUNG ADENOCARCINOMAS AXIN2, CTNND1, WNT1 PORCN 452/4885WNT3A 5/4885PSEN1 3911/4885
US-20260002121-A1 IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES BMP4, RARB, WNT3A PORCN 3877/4885WNT3A 3/4885PSEN1 4035/4885
US-12570956-B2 Efficient derivation of stable pluripotent bovine embryonic stem cells WNT1, PHKA1, ACVR1 PORCN 4724/4885WNT3A 5/4885PSEN1 2160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.