SCHEMBL29353028

SCHEMBL29353028

CSCCC1NC(=O)C(NC(=O)C(CCCNC(=N)N)NC(=O)C(CCSC)NC(=O)C(NC(=O)C(N)CC(=O)O)C(C)O)CSSCC(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)O)C(C)C)NC(=O)C2CCCN2C(=O)C(CCCNC(=N)N)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(C(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(C(C)C)NC1=O

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F12 P00748 8/20 0.57
F11 P03951 3/20 0.56
ALB P02768 1/20 0.56
TSLP Q969D9 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
MC4R P32245 1/20 0.54
MC3R P41968 1/20 0.54
MC1R Q01726 1/20 0.54
PRLHR P49683 2/20 0.53
EPHA2 P29317 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374066 0.87 MC4R (0.53) F12ALBTSLPRXFP1MC4R
SCHEMBL30893931 0.84 F12 (0.55) F12TSLPMC4RMC3RMC1R
SCHEMBL29462295 0.80 MC4R (0.70) F12F11RXFP1MC4RMC3R
SCHEMBL15987187 0.80 F12 (0.67) F12
SCHEMBL29389059 0.78 KCNMA1 (0.66) F11TSLPRXFP1PRLHR
SCHEMBL24256559 0.78 MC4R (0.61) F11RXFP1MC4RMC3RMC1R
SCHEMBL24256618 0.78 MC4R (0.63) F11MC4RMC3RMC1R
Polyphemusin Ii SCHEMBL29449206 0.78 F12 (0.62) F12MC4RMC1R
SCHEMBL31017614 0.77 KLKB1 (0.58) F12EPHA2
SCHEMBL27179393 0.77 MC4R (0.62) F11RXFP1MC4RMC3RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 826 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3532092-B1 IMMUNOGLOBULINS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2026-04-29 EP claimed
EP-4701663-A1 PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS, COMBINATIONS AND USES THEREOF Insilico Medicine IP Limited (HK) 2026-03-04 EP claimed
WO-2025229624-A2 NEW CD38 INHIBITORS NAPA THERAPEUTICS LIMITED (GB) 2025-11-06 WO claimed
EP-4615519-A2 TREATMENT OF NEUROLOGICAL DISORDER USING NHR Ocugen, Inc. (US) 2025-09-17 EP claimed
EP-3787631-B1 MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS UNIV EMORY (US) 2025-09-10 EP claimed
WO-2025133225-A1 PHARMACEUTICAL COMBINATION OF PEPTIDE-GLY AND PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE (PAM) PAM THERAGNOSTICS GMBH (DE) 2025-06-26 WO claimed
CN-120091835-A Treatment of neurological disorders using NHR 奥古根有限公司 2025-06-03 CN claimed
US-12318393-B2 Modulators of orphan nuclear receptors for NASH and other metabolic disorders EMORY UNIVERSITY 2025-06-03 US claimed
US-12297227-B2 Method for extracting target protein from biological sample and method for analyzing target protein MEDIFORD CORPORATION (JP) 2025-05-13 US claimed
US-12247064-B2 Modified ligand-gated ion channels and methods of use HOWARD HUGHES MEDICAL INSTITUTE (US) 2025-03-11 US claimed
EP-3878859-B1 NOVEL OXYNTOMODULIN DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR TREATING OBESITY COMPRISING THE SAME HANMI SCIENCE CO LTD (KR) 2023-11-01 EP claimed
WO-2023196866-A1 ENGINEERED CD200R ANTIBODIES AND USES THEREOF MIROBIO LIMITED (GB) 2023-10-12 WO claimed
US-20230314412-A1 Neuronal diencephalon stem cells, preparation and uses for treatment and prevention of hormonal disorders and other diseases FLORICA THERAPEUTICS INC (US) 2023-10-05 US claimed
US-11667688-B2 Glucagon derivative and a composition comprising a long acting conjugate of the same HANMI PHARM. CO., LTD. (KR) 2023-06-06 US claimed
CN-108495929-B Differentiation induction into hypothalamic neurons by human pluripotent stem cells 国立大学法人名古屋大学 2023-04-18 CN claimed
US-11401315-B2 Immunoglobulins and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2022-08-02 US claimed
US-20220127325-A1 GLUCAGON DERIVATIVE AND A COMPOSITION COMPRISING A LONG ACTING CONJUGATE OF THE SAME HANMI PHARM. CO., LTD. (KR) 2022-04-28 US claimed
US-11261227-B2 Glucagon derivative and a composition comprising a long acting conjugate of the same HANMI PHARM. CO., LTD. (KR) 2022-03-01 US claimed
US-11254724-B2 Glucagon derivatives HANMI PHARM. CO., LTD. (KR) 2022-02-22 US claimed
US-20220025012-A1 GLUCAGON DERIVATIVES HANMI PHARM IND CO LTD (KR) 2022-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12247064-B2 Modified ligand-gated ion channels and methods of use GRIK4, GRIK2, GRIK5 F12 4718/4885F11 4632/4885ALB 3806/4885
US-12318393-B2 Modulators of orphan nuclear receptors for NASH and other metabolic disorders RORA, RORB, RORC F12 4860/4885F11 4715/4885ALB 2077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.