SCHEMBL29389059

SCHEMBL29389059

CSCCC(NC(=O)C1CSSCC(NC(=O)C(NC(=O)C(CO)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C2CSSCC(NC(=O)C(CC(=O)O)NC(=O)C(NC(=O)C(CC(=O)O)NC(=O)C(NC(=O)C(Cc3ccccc3)NC(=O)C3CCC(=O)N3)C(C)O)C(C)C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)N2)C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(Cc2ccccc2)C(=O)NCC(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CCCCN)C(=O)N1)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC1CSSCC(C(=O)NC(Cc2ccc(O)cc2)C(=O)NC(CCC(N)=O)C(=O)O)NC(=O)C(CCCNC(=N)N)NC1=O

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 1/20 0.66
KCNMB4 Q86W47 1/20 0.66
RXFP1 Q9HBX9 1/20 0.65
RXFP4 Q8TDU9 5/20 0.61
RXFP3 Q9NSD7 5/20 0.61
TSLP Q969D9 3/20 0.59
GLP1R P43220 2/20 0.57
GCGR P47871 2/20 0.57
F11 P03951 1/20 0.57
NR3C1 P04150 1/20 0.56
NPR1 P16066 1/20 0.55
NPR3 P17342 1/20 0.55
BECN1 Q14457 3/20 0.55
BCL2L1 Q07817 1/20 0.55
BAD Q92934 1/20 0.55
PRLHR P49683 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29424808 0.85 RXFP1 (0.67) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29438822 0.81 KCNMA1 (0.66) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29369035 0.80 KCNMA1 (0.67) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29356518 0.80 KCNMA1 (0.59) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29353028 0.78 F12 (0.57) RXFP1TSLPF11PRLHR
SCHEMBL29462295 0.78 MC4R (0.70) KCNMA1KCNMB4RXFP1F11
SCHEMBL29607029 0.77 CSNK2A2 (0.67) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29471038 0.77 SSTR2 (0.60) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL29375073 0.76 NPR1 (0.59) KCNMA1KCNMB4RXFP1RXFP4RXFP3
SCHEMBL14190135 0.76 PRLHR (0.58) KCNMA1KCNMB4RXFP4RXFP3TSLP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213627-A1 RECOMBINANT MICROORGANISM-BASED METHODS AND COMPOSITIONS FOR TREATMENT OF DISEASE BAYLOR COLLEGE OF MEDICINE (US) 2025-07-03 US claimed
EP-4367217-A1 RECOMBINANT MICROORGANISM-BASED METHODS AND COMPOSITIONS FOR TREATMENT OF DISEASE Baylor College of Medicine (US) 2024-05-15 EP claimed
US-20230042176-A1 METHOD FOR TREATING ANGELMAN SYNDROME AND RELATED DISORDERS NAT UNIV SINGAPORE (SG) 2023-02-09 US claimed
WO-2023283646-A1 RECOMBINANT MICROORGANISM-BASED METHODS AND COMPOSITIONS FOR TREATMENT OF DISEASE BAYLOR COLLEGE OF MEDICINE (US) 2023-01-12 WO claimed
EP-4076471-A1 METHOD FOR TREATING ANGELMAN SYNDROME AND RELATED DISORDERS National University of Singapore (SG) 2022-10-26 EP claimed
US-12606937-B2 Humanized antibodies with ultralong complementary determining regions TAURUS BIOSCIENCES, LLC (US) 2026-04-21 US disclosed
US-20260008748-A1 COMPOUNDS WITH BIGUANIDYL RADICAL AND USES THEREOF INST CURIE (FR) 2026-01-08 US disclosed
US-20250376494-A1 INSECTICIDAL CYSTEINE RICH PEPTIDE EXPRESSION IN PLANTS Vestaron Corporation (US) 2025-12-11 US disclosed
WO-2025227157-A1 MODIFIED CELLS AND USES THEREOF UNIVERSITY OF MIAMI (US) 2025-10-30 WO disclosed
US-12433949-B2 Sustained release delivery systems comprising traceless linkers NOVARTIS AG (CH) 2025-10-07 US disclosed
US-20250292865-A1 DETERMINING BIOLOGICAL PARAMETERS OF A CELL THE UNIVERSITY OF BATH (GB) 2025-09-18 US disclosed
US-12415781-B2 Compounds with biguanidyl radical and uses thereof INSTITUT CURIE (FR) 2025-09-16 US disclosed
US-20220193096-A1 INHIBITORS OF NCCA-ATP CHANNELS FOR THERAPY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2022-06-23 US disclosed
US-20220143129-A1 METHODS AND COMPOSITIONS FOR TREATING MUCOSAL TISSUE DISORDERS UNIV NORTH CAROLINA CHAPEL HILL (US) 2022-05-12 US disclosed
US-20220133849-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF SMOOTH MUSCLE DYSFUNCTION UROVANT SCIENCES GMBH (CH) 2022-05-05 US disclosed
US-20220127337-A1 Anti-Viroporin Antibodies and Methods of Treating COVID-19 UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2022-04-28 US disclosed
US-11278595-B2 Peptides comprising non-natural amino acids and methods of making and using the same LONGEVITY BIOTECH, INC. (US) 2022-03-22 US disclosed
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2022-02-24 US disclosed
US-11246858-B2 Immunoresponsive methods of treating tumors INSTITUT PASTEUR DE MONTEVIDEO (UY) 2022-02-15 US disclosed
US-11246879-B2 Methods, agents, and devices for local neuromodulation of autonomic nerves Tulai Therapeutics, Inc. (US) 2022-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606937-B2 Humanized antibodies with ultralong complementary determining regions IGLV6-57, FCGR3B, VSIR KCNMA1 2682/4885KCNMB4 742/4885RXFP1 1234/4885
US-12415781-B2 Compounds with biguanidyl radical and uses thereof OGG1, MGMT, DPYD KCNMA1 2159/4885KCNMB4 1839/4885RXFP1 2761/4885
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 KCNMA1 3102/4885KCNMB4 3173/4885RXFP1 1794/4885
US-20230042176-A1 METHOD FOR TREATING ANGELMAN SYNDROME AND RELATED DISORDERS UBE3A, UBE3C, UBQLN1 KCNMA1 20/4885KCNMB4 82/4885RXFP1 2027/4885
US-20260008748-A1 COMPOUNDS WITH BIGUANIDYL RADICAL AND USES THEREOF CBR3, ROS1, CBR1 KCNMA1 1156/4885KCNMB4 611/4885RXFP1 3033/4885
US-12433949-B2 Sustained release delivery systems comprising traceless linkers ABCB11, ABCB1, GHRHR KCNMA1 4420/4885KCNMB4 3598/4885RXFP1 714/4885
US-11278595-B2 Peptides comprising non-natural amino acids and methods of making and using the same APLNR, SCTR, GIPR KCNMA1 3003/4885KCNMB4 3689/4885RXFP1 98/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.