SCHEMBL29355358

SCHEMBL29355358

O=C(O)c1cc2ccccc2c(N=Nc2ccccc2)c1O.[Ba+2]

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.76
KMT2A Q03164 6/20 0.76
MAPT P10636 6/20 0.76
POLB P06746 3/20 0.76
ALDH1A1 P00352 3/20 0.76
L3MBTL1 Q9Y468 3/20 0.76
RECQL P46063 2/20 0.76
MAPK1 P28482 2/20 0.76
KDM4E B2RXH2 1/20 0.76
NPC1 O15118 1/20 0.76
IDO1 P14902 1/20 0.76
CASP6 P55212 1/20 0.76
CTDSP1 Q9GZU7 1/20 0.76
TDP1 Q9NUW8 3/20 0.74
MITF O75030 1/20 0.74
USP2 O75604 1/20 0.74
MPL P40238 1/20 0.63
NQO2 P16083 1/20 0.56
CYP1A2 P05177 2/20 0.55
GPR35 Q9HC97 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343952 0.98 MEN1 (0.78) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL343951 0.98 MEN1 (0.78) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL29582683 0.98 MEN1 (0.78) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL9577924 0.97 MEN1 (0.76) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL5351789 0.90 MEN1 (0.71) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL5351787 0.90 MEN1 (0.71) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL29598421 0.89 MEN1 (0.65) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL92098 0.87 KMT2A (0.80) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL825871 0.87 MEN1 (0.67) MEN1KMT2AMAPTPOLBALDH1A1
SCHEMBL8639473 0.87 MEN1 (0.68) MEN1KMT2AMAPTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12364659-B2 Multicomponent in situ coloration composition WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2025-07-22 US disclosed
US-20250195400-A1 PIGMENT DISPERSIONS WITH HYDROPHOBIC POLYMER L'OREAL (FR) 2025-06-19 US disclosed
US-20250114287-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2025-04-10 US disclosed
US-12201714-B2 Multicomponent pur composition WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2025-01-21 US disclosed
US-20240261213-A1 MULTICOMPONENT PUR COMPOSITION Wella International Operations Switzerland Sárl (CH) 2024-08-08 US disclosed
US-12053542-B2 Multicomponent silicone composition WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-08-06 US disclosed
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMINY GMBH (DE) 2023-10-05 US disclosed
US-11697743-B2 Ink composition, writing instrument and method for producing ink composition PENTEL KABUSHIKI KAISHA 2023-07-11 US disclosed
EP-4171500-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER Wella Germany GmbH (DE) 2023-05-03 EP disclosed
US-11613663-B2 Ink composition, writing tool and method for producing ink composition PENTEL KABUSHIKI KAISHA 2023-03-28 US disclosed
US-11478415-B2 Multicomponent composition WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2022-10-25 US disclosed
US-11324688-B2 Bicomponent composition WELLA INTERNATIONAL OPERATIONS SWI (CH) 2022-05-10 US disclosed
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2022-02-24 US disclosed
US-11229584-B2 Pigment dispersion liquid for cosmetics, and aqueous liquid cosmetic using same MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2022-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195400-A1 PIGMENT DISPERSIONS WITH HYDROPHOBIC POLYMER TYR, MC1R, ALAD MEN1 320/4885KMT2A 2780/4885MAPT 2778/4885
US-20250114287-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES KRT18, ITGA5, FLNA MEN1 2431/4885KMT2A 586/4885MAPT 360/4885
US-12053542-B2 Multicomponent silicone composition CUTA, CD99, PLOD3 MEN1 10/4885KMT2A 648/4885MAPT 2078/4885
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER KRT18, MKI67, IK MEN1 811/4885KMT2A 876/4885MAPT 621/4885
US-12364659-B2 Multicomponent in situ coloration composition KRT18, PRKDC, VIM MEN1 1309/4885KMT2A 1653/4885MAPT 817/4885
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION KRT18, PRKDC, VIM MEN1 1309/4885KMT2A 1653/4885MAPT 817/4885
US-11324688-B2 Bicomponent composition KRT18, EXOSC10, EXOSC9 MEN1 1869/4885KMT2A 1253/4885MAPT 1247/4885
US-12201714-B2 Multicomponent pur composition KRT18, EXOSC9, EXOSC4 MEN1 967/4885KMT2A 1904/4885MAPT 2254/4885
US-20240261213-A1 MULTICOMPONENT PUR COMPOSITION KRT18, EXOSC9, EXOSC4 MEN1 967/4885KMT2A 1904/4885MAPT 2254/4885
US-11478415-B2 Multicomponent composition KRT18, INCENP, IK MEN1 585/4885KMT2A 684/4885MAPT 1146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.