SCHEMBL29359151

SCHEMBL29359151

COc1ccccc1[P@](CC[P@](c1ccccc1)c1ccccc1OC)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.44
CA2 P00918 4/20 0.44
CA7 P43166 3/20 0.44
CA9 Q16790 3/20 0.44
CA12 O43570 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA4 P22748 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.38
POLB P06746 1/20 0.38
ALDH1A1 P00352 2/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
ADRA2B P18089 1/20 0.38
PTGS1 P23219 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HTT P42858 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPK1 P28482 1/20 0.36
IDO1 P14902 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367537 1.00 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL29396701 1.00 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL30517362 1.00 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL31593 1.00 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL30007746 1.00 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL1231880 1.00 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL10290527 1.00 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL29930052 1.00 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL903333 1.00 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL42030 1.00 CA1 (0.44) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3894390-B1 SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF HEIDELBERG PHARMA RES GMBH (DE) 2026-05-20 EP claimed
US-12378196-B2 Synthesis of (S)-6-hydroxytryptophan and derivatives thereof HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-08-05 US claimed
US-20250179018-A1 SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-05 US claimed
EP-3694864-B1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA INC (US) 2025-03-05 EP claimed
CN-119462502-A Tenapanol Process for the preparation of intermediates 杭州善礼生物医药科技有限公司 2025-02-18 CN claimed
US-11286270-B2 Boronic acid derivatives and synthesis thereof QPEX BIOPHARMA, INC. (US) 2022-03-29 US claimed
US-20220024870-A1 Synthesis of (S)-6-Hydroxytryptophan and Derivatives Thereof HEIDELBERG PHARMA RESEARCH GMBH (DE) 2022-01-27 US claimed
EP-3894390-B1 SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF HEIDELBERG PHARMA RES GMBH (DE) 2026-05-20 EP disclosed
EP-3210965-B2 PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL GRUENENTHAL GMBH (DE) 2026-05-13 EP disclosed
US-12552815-B2 Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2026-02-17 US disclosed
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES BHATTACHARYA SHRABANTI (US) 2025-12-04 US disclosed
US-12378196-B2 Synthesis of (S)-6-hydroxytryptophan and derivatives thereof HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-08-05 US disclosed
US-20250179018-A1 SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-05 US disclosed
US-20230220001-A1 METHOD FOR SYNTHESIS OF THIOETHER-CONTAINING PEPTIDES HEIDELBERG PHARMA RESEARCH GMBH (DE) 2023-07-13 US disclosed
EP-4149949-A1 BORONIC ACID DERIVATIVES AND SYNTHESIS, POLYMORPHIC FORMS, AND THERAPEUTIC USES THEREOF QPEX BIOPHARMA, INC. (US) 2023-03-22 EP disclosed
WO-2022253111-A1 METHOD FOR USING REDUCTION TO PREPARE (S)-NICOTINE 重庆博腾制药科技股份有限公司 2022-12-08 WO disclosed
CN-110669073-B Phosphaphenanthrene tertiary phosphine derivative, and synthesis method and application thereof 聊城大学 2022-10-11 CN disclosed
US-11286270-B2 Boronic acid derivatives and synthesis thereof QPEX BIOPHARMA, INC. (US) 2022-03-29 US disclosed
CN-113999201-A Synthetic preparation method of nicotine 成昌梅 2022-02-01 CN disclosed
US-20220024870-A1 Synthesis of (S)-6-Hydroxytryptophan and Derivatives Thereof HEIDELBERG PHARMA RESEARCH GMBH (DE) 2022-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES CA4, CA12, CA14 CA1 9/4885CA2 8/4885CA7 5/4885
US-20220024870-A1 Synthesis of (S)-6-Hydroxytryptophan and Derivatives Thereof AANAT, HNMT, HTR6 CA1 2500/4885CA2 2864/4885CA7 2098/4885
US-20230220001-A1 METHOD FOR SYNTHESIS OF THIOETHER-CONTAINING PEPTIDES TST, PTMS, CTH CA1 492/4885CA2 1978/4885CA7 1429/4885
US-20250179018-A1 SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF AANAT, HNMT, HTR6 CA1 3045/4885CA2 3656/4885CA7 2844/4885
US-12378196-B2 Synthesis of (S)-6-hydroxytryptophan and derivatives thereof AANAT, HNMT, HTR6 CA1 2500/4885CA2 2864/4885CA7 2098/4885
US-11286270-B2 Boronic acid derivatives and synthesis thereof BTD, BLVRB, BLK CA1 1169/4885CA2 425/4885CA7 89/4885
US-12552815-B2 Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof BBC3, BLK, BRCA1 CA1 3661/4885CA2 330/4885CA7 437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.