Nocodazole

Nocodazole

SCHEMBL29360101

COC(=O)Nc1nc2cc(C(=O)c3cccs3)ccc2[nH]1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 3/20 0.84
ALDH1A1 P00352 2/20 0.84
LMNA P02545 2/20 0.84
CYP1A2 P05177 2/20 0.84
CYP2C9 P11712 2/20 0.84
HTT P42858 2/20 0.84
HIF1A Q16665 2/20 0.84
TUBB4A P04350 2/20 0.84
TUBB P07437 2/20 0.84
TUBA3C P0DPH7 2/20 0.84
TUBA1B P68363 2/20 0.84
TUBA4A P68366 2/20 0.84
TUBB4B P68371 2/20 0.84
TUBB3 Q13509 2/20 0.84
TUBB2A Q13885 2/20 0.84
TUBB8 Q3ZCM7 2/20 0.84
TUBA3E Q6PEY2 2/20 0.84
TUBA1A Q71U36 2/20 0.84
TUBA1C Q9BQE3 2/20 0.84
TUBB6 Q9BUF5 2/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nocodazole SCHEMBL9477 1.00 ABL1 (0.84) ABL1ALDH1A1LMNACYP1A2CYP2C9
Nocodazole SCHEMBL8009081 1.00 ABL1 (0.84) ABL1ALDH1A1LMNACYP1A2CYP2C9
Nocodazole SCHEMBL7615542 0.99 ABL1 (0.82) ABL1ALDH1A1LMNACYP1A2CYP2C9
Nocodazole SCHEMBL8198291 0.96 ABL1 (0.77) ABL1ALDH1A1LMNACYP1A2CYP2C9
Nocodazole SCHEMBL8195415 0.96 ABL1 (0.77) ABL1ALDH1A1LMNACYP1A2CYP2C9
Nocodazole SCHEMBL22418403 0.95 ABL1 (0.76) ABL1ALDH1A1LMNACYP1A2CYP2C9
Nocodazole SCHEMBL29573963 0.91 ABL1 (1.00) ABL1ALDH1A1LMNACYP1A2CYP2C9
Nocodazole SCHEMBL2324427 0.91 ABL1 (1.00) ABL1ALDH1A1LMNACYP1A2CYP2C9
Nocodazole SCHEMBL8186933 0.90 ABL1 (0.68) ABL1ALDH1A1LMNACYP1A2CYP2C9
SCHEMBL4204424 0.87 NPC1 (0.64) ABL1ALDH1A1LMNACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295787-A1 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-09-25 US claimed
EP-3612231-B1 DRUG DELIVERY SYSTEM LIPOGEMS INT S P A (IT) 2025-06-25 EP claimed
EP-4086250-B1 MULTIFUNCTIONAL INHIBITORS OF MEK/PI3K AND MTOR/MEK/PI3K BIOLOGICAL PATHWAYS AND THERAPEUTIC METHODS USING THE SAME UNIV MICHIGAN REGENTS (US) 2024-12-11 EP claimed
EP-4011887-B1 COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY CALITHERA BIOSCIENCES INC (US) 2024-07-31 EP claimed
EP-3888658-B1 EIF4-A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO EFFECTOR THERAPEUTICS INC (US) 2023-12-27 EP claimed
US-20230405156-A1 METHODS OF DIAGNOSING AND PROGNOSING CANCERS OF THE HEAD AND NECK THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-12-21 US claimed
EP-3313443-B9 COMBINING ANTI-HLA-DR OR ANTI-TROP-2 ANTIBODIES WITH MICROTUBULE INHIBITORS, PARP INHIBITORS, BRUTON KINASE INHIBITORS OR PHOSPHOINOSITIDE 3-KINASE INHIBITORS SIGNIFICANTLY IMPROVES THERAPEUTIC OUTCOME IN CANCER IMMUNOMEDICS INC (US) 2023-10-04 EP claimed
EP-3313443-B1 COMBINING ANTI-HLA-DR OR ANTI-TROP-2 ANTIBODIES WITH MICROTUBULE INHIBITORS, PARP INHIBITORS, BRUTON KINASE INHIBITORS OR PHOSPHOINOSITIDE 3-KINASE INHIBITORS SIGNIFICANTLY IMPROVES THERAPEUTIC OUTCOME IN CANCER IMMUNOMEDICS INC (US) 2023-06-07 EP claimed
EP-3021832-B9 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-03-15 EP claimed
EP-3441089-B1 TREATMENT METHODS USING ADENOVIRUS VASCULAR BIOGENICS LTD (IL) 2022-12-14 EP claimed
EP-3166976-B1 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS INC (KY) 2022-02-23 EP claimed
EP-3693375-B1 COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY CALITHERA BIOSCIENCES INC (US) 2022-02-16 EP claimed
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP disclosed
EP-4748838-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-27 EP disclosed
US-12637510-B2 Oncolytic virus compositions and methods for the treatment of cancer CITY OF HOPE (US) 2026-05-26 US disclosed
US-12630527-B2 Broad spectrum anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-19 US disclosed
WO-2022031952-A2 TREATMENTS FOR CANCERS HAVING KRAS MUTATIONS CITY OF HOPE (US) 2022-02-10 WO disclosed
WO-2022023772-A1 ANTAGONIST COMPOUNDS AdoRx Therapeutics Limited (GB) 2022-02-03 WO disclosed
US-20220023307-A1 METHOD OF TREATING METASTATIC CANCER IN A SUBJECT WITH A PROTEIN INHIBITOR CITY UNIVERSITY OF HONG KONG (HK) 2022-01-27 US disclosed
EP-3941905-A1 SUMO INHIBITOR COMPOUNDS AND USES THEREOF Suvalent Therapeutics, Inc. (US) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637510-B2 Oncolytic virus compositions and methods for the treatment of cancer CD47, IGLV6-57, STING1 ABL1 1509/4885ALDH1A1 4561/4885LMNA 3051/4885
US-12630527-B2 Broad spectrum anti-cancer compounds YTHDF3, YTHDF1, YTHDF2 ABL1 162/4885ALDH1A1 4643/4885LMNA 3347/4885
US-20220023307-A1 METHOD OF TREATING METASTATIC CANCER IN A SUBJECT WITH A PROTEIN INHIBITOR NCBP1, NCBP2, CAPN9 ABL1 3258/4885ALDH1A1 4456/4885LMNA 2853/4885
US-20250295787-A1 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION SI, PIM1, PIM3 ABL1 3019/4885ALDH1A1 3167/4885LMNA 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.