SCHEMBL29367000

SCHEMBL29367000

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(C)C)NC(=O)[C@@H]3CCCN3C(=O)[C@@H]3CCC(=O)N3)CSSC[C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC2=O)C(=O)N[C@@H](CO)C(=O)N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O

nearest known ligand 0.68

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPY2R P49146 12/20 0.68
PRLHR P49683 6/20 0.68
NPFFR2 Q9Y5X5 1/20 0.65
INSR P06213 1/20 0.64
RAMP1 O60894 1/20 0.62
RAMP2 O60895 1/20 0.62
RAMP3 O60896 1/20 0.62
CALCR P30988 1/20 0.62
CALCRL Q16602 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366836 0.90 HCRTR1 (0.68) NPY2RPRLHRRAMP1RAMP2RAMP3
Davalintide SCHEMBL29533482 0.81 RAMP1 (0.77) NPY2RPRLHRINSRRAMP1RAMP2
SCHEMBL33618 0.80 INSR (0.75) NPY2RPRLHRNPFFR2INSR
SCHEMBL15669703 0.80 INSR (0.95) NPY2RINSR
SCHEMBL30888738 0.80 NPY2R (0.63) NPY2RINSRRAMP1RAMP2RAMP3
SCHEMBL14840198 0.80 INSR (0.93) NPY2RINSRRAMP1RAMP2RAMP3
SCHEMBL63125 0.79 INSR (0.98) NPY2RINSR
SCHEMBL29511605 0.79 RAMP1 (0.71) NPY2RPRLHRINSRRAMP1RAMP2
Calcitonin Salmon SCHEMBL269785 0.78 INSR (0.64) NPY2RINSRRAMP1RAMP2RAMP3
SCHEMBL374892 0.78 RAMP1 (0.78) NPY2RPRLHRNPFFR2INSRRAMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260131089-A1 DRUG DELIVERY DEVICES AND METHODS FOR ADMINISTERING SUBSTANCES TO A BODY CAVITY BY HETEROGENOUS AEROSOLIZATION FOR TREATMENT OF BINGE-EATING DISORDERS AND/OR OBESITY APTARGROUP, INC. (US) 2026-05-14 US claimed
US-12491325-B2 Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization for treatment of binge-eating disorders and/or obesity APTARGROUP, INC. (US) 2025-12-09 US claimed
US-20250325760-A1 DRUG DELIVERY DEVICES AND METHODS FOR ADMINISTERING SUBSTANCES TO A BODY CAVITY BY HETEROGENOUS AEROSOLIZATION APTARGROUP INC. (US) 2025-10-23 US claimed
WO-2025133225-A1 PHARMACEUTICAL COMBINATION OF PEPTIDE-GLY AND PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE (PAM) PAM THERAGNOSTICS GMBH (DE) 2025-06-26 WO claimed
WO-2025137359-A1 ASSAY METHODS TO IDENTIFY A DISEASE EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-06-26 WO claimed
US-12329902-B2 Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization SIPNOSE LTD. (IL) 2025-06-17 US claimed
CN-119587679-A Use of Orexin-A for inhibiting lipid peroxidation 贵州医科大学附属医院 2025-03-11 CN claimed
CN-119185569-A Sustained release delivery system comprising a traceless linker 诺华股份有限公司 2024-12-27 CN claimed
US-20240180972-A1 HUMAN PLURIPOTENT STEM CELL-DERIVED SECRETOME AS A BIOLOGIC FOR PREVENTION AND TREATMENT OF NEURODEGENERATIVE AND APOPTOTIC DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-06 US claimed
US-11992604-B2 Devices and methods for delivering a substance to a body cavity SIPNOSE LTD. (IL) 2024-05-28 US claimed
EP-4243993-A1 DEVICES AND METHODS FOR DELIVERING A SUBSTANCE TO A BODY CAVITY Sipnose Ltd (IL) 2023-09-20 EP claimed
US-11730904-B2 Intranasal administration Optinose, Inc. (US) 2023-08-22 US claimed
US-11707586-B2 Intranasal administration OptiNose Inc. (US) 2023-07-25 US claimed
EP-4114485-A1 DEVICES AND METHODS FOR DELIVERING A SUBSTANCE TO A BODY CAVITY Sipnose Ltd (IL) 2023-01-11 EP claimed
WO-2022212878-A1 HUMAN PLURIPOTENT STEM CELL-DERIVED SECRETOME AS A BIOLOGIC FOR PREVENTION AND TREATMENT OF NEURODEGENERATIVE AND APOPTOTIC DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-10-06 WO claimed
WO-2022101851-A1 DEVICES AND METHODS FOR DELIVERING A SUBSTANCE TO A BODY CAVITY SIPNOSE LTD. (IL) 2022-05-19 WO claimed
WO-2022101850-A1 DEVICES AND METHODS FOR DELIVERING A SUBSTANCE TO A BODY CAVITY SIPNOSE LTD. (IL) 2022-05-19 WO claimed
US-20220032021-A1 DEVICES AND METHODS FOR DELIVERING A SUBSTANCE TO A BODY CAVITY SIPNOSE LTD. (IL) 2022-02-03 US claimed
WO-2026106499-A1 OREXIN RECEPTOR ANTAGONISTS: 2-AZABICYCLIC COMPOUNDS BIAL - PORTELA & CA., S.A. (PT) 2026-05-21 WO disclosed
CN-109988169-B Octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof 广东东阳光药业有限公司 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260131089-A1 DRUG DELIVERY DEVICES AND METHODS FOR ADMINISTERING SUBSTANCES TO A BODY CAVITY BY HETEROGENOUS AEROSOLIZATION FOR TREATMENT OF BINGE-EATING DISORDERS AND/OR OBESITY CACNG6, MC5R, CRH NPY2R 25/4885PRLHR 632/4885NPFFR2 334/4885
US-12491325-B2 Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization for treatment of binge-eating disorders and/or obesity GCG, VAPA, GABRG2 NPY2R 207/4885PRLHR 210/4885NPFFR2 484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.