SCHEMBL374892

SCHEMBL374892

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O)C(C)C)[C@@H](C)O

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RAMP1 O60894 1/20 0.78
RAMP2 O60895 1/20 0.78
RAMP3 O60896 1/20 0.78
CALCR P30988 1/20 0.78
CALCRL Q16602 1/20 0.78
NPY2R P49146 12/20 0.66
PRLHR P49683 4/20 0.62
INSR P06213 1/20 0.62
GLP1R P43220 1/20 0.60
NPFFR2 Q9Y5X5 1/20 0.60
RXFP1 Q9HBX9 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amylin SCHEMBL29351499 0.98 RAMP1 (0.75) RAMP1RAMP2RAMP3CALCRCALCRL
Davalintide SCHEMBL29533482 0.89 RAMP1 (0.77) RAMP1RAMP2RAMP3CALCRCALCRL
Pramlintide SCHEMBL29355376 0.88 RAMP1 (1.00) RAMP1RAMP2RAMP3CALCRCALCRL
Pramlintide SCHEMBL29354060 0.87 RAMP1 (0.99) RAMP1RAMP2RAMP3CALCRCALCRL
SCHEMBL30078470 0.87 RAMP1 (0.91) RAMP1RAMP2RAMP3CALCRCALCRL
SCHEMBL29511605 0.85 RAMP1 (0.71) RAMP1RAMP2RAMP3CALCRCALCRL
Davalintide SCHEMBL29377013 0.83 RAMP1 (0.85) RAMP1RAMP2RAMP3CALCRCALCRL
SCHEMBL29357151 0.83 RAMP1 (0.68) RAMP1RAMP2RAMP3CALCRCALCRL
SCHEMBL31692974 0.81 RAMP1 (0.82) RAMP1RAMP2RAMP3CALCRCALCRL
SCHEMBL29382043 0.79 GLP1R (0.80) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1726 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122074076-A Peptides for detection of amyloid fibril aggregates 乌特勒支大学 2026-05-22 CN claimed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP claimed
EP-4705280-A1 DIARYL UREA-BASED COMPOUNDS AND RELATED COMPOSITIONS AND METHODS OF USE IN THE TREATMENT OF DIABETES MELLITUS AND NEURODEGENERATIVE DISEASE Purdue Research Foundation (US) 2026-03-11 EP claimed
EP-4705326-A1 GENE THERAPY FOR TREATMENT OF PROTEIN MISFOLDING DISEASES Research Institute at Nationwide Children's Hospital (US) 2026-03-11 EP claimed
US-20260043815-A1 METHODS FOR DETECTING B-ISOX PRECIPITATES OR CAPTURED PROTEINS AS BIOFLUID BIOMARKERS FOR DIFFERENTIAL DIAGNOSTIC, PATHOPHYSIOLOGY MONITORING OR PRESYMPTOMATIC DIAGNOSTIC OF PREDIABETES, DIABETES AND CANCERS YEEFAN MED INC (US) 2026-02-12 US claimed
EP-4686725-A1 AMYLOID INHIBITORY PEPTIDES Technische Universität München, in Vertretung des Freistaats Bayern (DE) 2026-02-04 EP claimed
US-12502114-B2 Amyloid fibers based electrodes Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2025-12-23 US claimed
US-20250321237-A1 ASSAY FOR RAPID PROTEIN MULTIMER DETECTION, CHARACTERIZATION AND QUANTIFICATION WESTERN MICHIGAN UNIVERSITY HOMER STRYKER M.D. SCHOOL OF MEDICINE (US) 2025-10-16 US claimed
EP-4611818-A2 ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS Avilar Therapeutics, Inc. (US) 2025-09-10 EP claimed
US-20250270319-A1 ANTI-CD33 ANTIBODIES AND METHODS OF USE THEREOF ALECTOR LLC (US) 2025-08-28 US claimed
WO-2022094630-A1 SAP FC FUSION PROTEINS AND METHODS OF USE ATTRALUS, INC. (US) 2022-05-05 WO claimed
US-20220123377-A1 CONVECTION-ENHANCED ELECTROCHEMICAL ENERGY STORAGE DEVICES AND RELATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-04-21 US claimed
US-20220119468-A1 AMYLOID PEPTIDE VARIANTS LOYOLA MARYMOUNT UNIVERSITY 2022-04-21 US claimed
CN-114341181-A anti-MS 4A4A antibodies and methods of use thereof 艾莱克特有限责任公司 2022-04-12 CN claimed
US-20220090020-A1 DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-03-24 US claimed
CN-108884126-B Compounds for treating eye disorders or diseases 广州康睿生物医药科技股份有限公司 2022-03-18 CN claimed
US-20220040145-A1 INHIBITORS OF MICROBIALLY INDUCED AMYLOID AXIAL THERAPEUTICS, INC. 2022-02-10 US claimed
EP-3946385-A1 THE TREATMENT OF PROTEIN AGGREGATION DISEASES Pharmakure Limited (GB) 2022-02-09 EP claimed
WO-2022026933-A2 IN VITRO DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-02-03 WO claimed
WO-2022026932-A2 DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-02-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220090020-A1 DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS IAPP, PNLIP, GPR119 RAMP1 3743/4885RAMP2 3661/4885RAMP3 1955/4885
US-20220040145-A1 INHIBITORS OF MICROBIALLY INDUCED AMYLOID APP, PSEN1, BACE1 RAMP1 2362/4885RAMP2 3077/4885RAMP3 1755/4885
US-20260043815-A1 METHODS FOR DETECTING B-ISOX PRECIPITATES OR CAPTURED PROTEINS AS BIOFLUID BIOMARKERS FOR DIFFERENTIAL DIAGNOSTIC, PATHOPHYSIOLOGY MONITORING OR PRESYMPTOMATIC DIAGNOSTIC OF PREDIABETES, DIABETES AND CANCERS IGFBP4, RBP4, IGFBP3 RAMP1 3621/4885RAMP2 3625/4885RAMP3 936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.