SCHEMBL29367495

SCHEMBL29367495

NNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.67
EPHX2 P34913 1/20 0.58
FABP5 Q01469 3/20 0.50
FABP7 O15540 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CASP3 P42574 2/20 0.48
MDM4 O15151 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31031957 1.00 KMT2A (0.67) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL401725 1.00 KMT2A (0.67) KMT2AEPHX2FABP5FABP7CA1
Hydrochloric Acid SCHEMBL1595146 0.98 KMT2A (0.65) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL27640993 0.88 KMT2A (0.57) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL21332462 0.86 KMT2A (0.66) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL18510206 0.85 KMT2A (0.61) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL30238049 0.85 KMT2A (0.64) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL1800381 0.85 KMT2A (0.64) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL25612527 0.84 KMT2A (0.68) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL1105520 0.84 KMT2A (0.63) KMT2AEPHX2FABP5FABP7CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 EP disclosed
US-12630601-B2 Process for preparing a GIP/GLP1 dual agonist ELI LILLY AND COMPANY (US) 2026-05-19 US disclosed
CN-122036701-A Responsive near infrared one-region fluorescent compound and preparation method and application thereof 中山大学 2026-05-15 CN disclosed
US-12624064-B2 Linker molecule and use thereof in methods for purifying peptides Gyros Protein Technologies AB (SE) 2026-05-12 US disclosed
US-12624079-B2 Process for preparing a GIP/GLP1 dual agonist ELI LILLY AND COMPANY (US) 2026-05-12 US disclosed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 US disclosed
EP-4685157-A2 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST Eli Lilly and Company (US) 2026-01-28 EP disclosed
EP-4685156-A2 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST Eli Lilly and Company (US) 2026-01-28 EP disclosed
WO-2023097407-A1 MODIFIED AMATOXINS AND USES THEREOF THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-06-08 WO disclosed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US disclosed
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-29 US disclosed
US-11440881-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-09-13 US disclosed
WO-2022163846-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE 第一三共株式会社 2022-08-04 WO disclosed
US-20220135639-A1 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST ELI LILLY AND COMPANY 2022-05-05 US disclosed
WO-2022054062-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2022-03-17 WO disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 EP disclosed
CN-113999289-A Preparation method of goserelin 杭州信海医药科技有限公司 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11440881-B2 Thiosemicarbazates and uses thereof TST, ABAT, AADAC KMT2A 1523/4885EPHX2 2881/4885FABP5 1137/4885
US-12624079-B2 Process for preparing a GIP/GLP1 dual agonist GLP1R, GIPR, GPR119 KMT2A 953/4885EPHX2 3646/4885FABP5 3546/4885
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 KMT2A 2546/4885EPHX2 2136/4885FABP5 2277/4885
US-12630601-B2 Process for preparing a GIP/GLP1 dual agonist GLP1R, GIPR, IAPP KMT2A 633/4885EPHX2 3203/4885FABP5 4570/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 KMT2A 2773/4885EPHX2 2419/4885FABP5 666/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC KMT2A 1523/4885EPHX2 2881/4885FABP5 1137/4885
US-20220135639-A1 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST GLP1R, GIPR, GPR119 KMT2A 2749/4885EPHX2 2562/4885FABP5 2754/4885
US-12624064-B2 Linker molecule and use thereof in methods for purifying peptides SPPL2B, SPPL2A, VIP KMT2A 4464/4885EPHX2 1193/4885FABP5 3278/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT KMT2A 2188/4885EPHX2 3200/4885FABP5 2296/4885
US-20220306577-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC KMT2A 1523/4885EPHX2 2881/4885FABP5 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.