SCHEMBL29368960

SCHEMBL29368960

Cc1cn([C@H]2C[C@H](OP(=O)(S)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)C[C@@H]3O)[C@@H](COP(=O)(S)O[C@H]3C[C@H](n4ccc(N)nc4=O)O[C@@H]3CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.60
▸ F2 P00734 2/20 0.57
▸ TERT O14746 2/20 0.52
▸ POLB P06746 2/20 0.47
▸ ENPP1 P22413 2/20 0.47
▸ P2RY1 P47900 1/20 0.47
▸ P2RY2 P41231 1/20 0.46
▸ P2RY4 P51582 1/20 0.46
▸ P2RY6 Q15077 1/20 0.46
▸ RNASEL Q05823 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14389953 1.00 DTYMK (0.60) DTYMKF2TERTPOLBENPP1
SCHEMBL13326136 1.00 DTYMK (0.60) DTYMKF2TERTPOLBENPP1
SCHEMBL10034039 1.00 DTYMK (0.60) DTYMKF2TERTPOLBENPP1
SCHEMBL14389886 1.00 DTYMK (0.60) DTYMKF2TERTPOLBENPP1
SCHEMBL26189527 0.96 F2 (0.64) DTYMKF2TERTPOLBENPP1
SCHEMBL26189524 0.96 F2 (0.64) DTYMKF2TERTPOLBENPP1
SCHEMBL21504636 0.96 F2 (0.64) DTYMKF2TERTPOLBENPP1
SCHEMBL21489387 0.96 F2 (0.64) DTYMKF2TERTPOLBENPP1
SCHEMBL30301232 0.94 DTYMK (0.65) DTYMKF2TERTPOLBENPP1
SCHEMBL29401735 0.94 DTYMK (0.65) DTYMKF2TERTPOLBENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773098-B2 Solid forms of a toll-like receptor modulator GILEAD SCIENCES, INC. (US) 2023-10-03 — — US claimed
CN-122036801-A Crystalline forms of tenofovir alafenamide 吉利德科学公司 2026-05-15 — — CN disclosed
EP-3870566-B1 PD-1/PD-L1 INHIBITORS GILEAD SCIENCES INC (US) 2026-05-06 — — EP disclosed
EP-4234030-B1 PD-1/PD-L1 INHIBITORS GILEAD SCIENCES INC (US) 2026-04-08 — — EP disclosed
US-12590062-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2026-03-31 — — US disclosed
US-20260028603-A1 ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR A RECOGNITION SEQUENCE IN THE HEPATITIS B VIRUS GENOME PRECISION BIOSCIENCES, INC. (US) 2026-01-29 — — US disclosed
US-12522570-B2 Toll like receptor modulator compounds GILEAD SCIENCES, INC. (US) 2026-01-13 — — US disclosed
EP-4667477-A2 PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE Gilead Sciences, Inc. (US) 2025-12-24 — — EP disclosed
US-12486271-B2 Solid forms of a toll-like receptor modulator GILEAD SCIENCES, INC. (US) 2025-12-02 — — US disclosed
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-11-27 — — US disclosed
US-20220143061-A1 3'3'-CYCLIC DINUCLEOTIDES AND PRODRUGS THEREOF INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) 2022-05-12 — — US disclosed
EP-3990476-A1 FLT3L-FC FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2022-05-04 — — EP disclosed
US-20220119426-A1 PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES, INC. 2022-04-21 — — US disclosed
US-20220117952-A1 METHODS FOR TREATING HEPATITIS B VIRUS INFECTIONS USING NS5A, NS5B OR NS3 INHIBITORS GILEAD SCIENCES, INC. 2022-04-21 — — US disclosed
US-11292812-B2 3′3′-cyclic dinucleotides INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) 2022-04-05 — — US disclosed
EP-3972695-A1 SUBSTITUTED EXO-METHYLENE-OXINDOLES WHICH ARE HPK1/MAP4K1 INHIBITORS Gilead Sciences, Inc. (US) 2022-03-30 — — EP disclosed
CN-114245807-A FLT3L-FC fusion proteins and methods of use 吉利德科学公司 2022-03-25 — — CN disclosed
US-20220073473-A1 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. 2022-03-10 — — US disclosed
US-20220049021-A1 FLT3L-Fc FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES, INC. 2022-02-17 — — US disclosed
US-11236085-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2022-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073473-A1 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS TLR8, TLR3, TLR6 DTYMK 1307/4885F2 4608/4885TERT 4237/4885
US-20220143061-A1 3'3'-CYCLIC DINUCLEOTIDES AND PRODRUGS THEREOF STING1, CGAS, IRF3 DTYMK 104/4885F2 3420/4885TERT 2067/4885
US-12486271-B2 Solid forms of a toll-like receptor modulator TLR4, TLR3, TLR6 DTYMK 1093/4885F2 2633/4885TERT 4559/4885
US-20220119426-A1 PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE PNP, TYMP, NME2 DTYMK 60/4885F2 2356/4885TERT 2354/4885
US-20220117952-A1 METHODS FOR TREATING HEPATITIS B VIRUS INFECTIONS USING NS5A, NS5B OR NS3 INHIBITORS HAVCR2, EIF2AK2, HPN DTYMK 2231/4885F2 4441/4885TERT 1656/4885
US-11773098-B2 Solid forms of a toll-like receptor modulator TLR4, TLR3, TLR6 DTYMK 1093/4885F2 2633/4885TERT 4559/4885
US-11292812-B2 3′3′-cyclic dinucleotides STING1, CGAS, MAVS DTYMK 24/4885F2 4672/4885TERT 2810/4885
US-12590062-B2 PD-1/PD-L1 inhibitors CD274, PDCD1LG2, PDCD1 DTYMK 3343/4885F2 4847/4885TERT 1253/4885
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS DGKG, DGKB, DGKK DTYMK 115/4885F2 4642/4885TERT 2753/4885
US-11236085-B2 PD-1/PD-L1 inhibitors PDCD1, CD274, PDCD1LG2 DTYMK 561/4885F2 3949/4885TERT 242/4885
US-20260028603-A1 ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR A RECOGNITION SEQUENCE IN THE HEPATITIS B VIRUS GENOME HAVCR2, PNP, ADAR DTYMK 448/4885F2 1115/4885TERT 1957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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