SCHEMBL29371752

SCHEMBL29371752

CC(=O)Oc1ccc(N=Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)cc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AMY1A P0DUB6 1/20 0.53
▸ GAA P10253 1/20 0.52
▸ KDR P35968 1/20 0.52
▸ LMNA P02545 2/20 0.48
▸ TSHR P16473 3/20 0.48
▸ THRB P10828 1/20 0.47
▸ ALDH1A1 P00352 2/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ RXFP1 Q9HBX9 1/20 0.46
▸ HPGD P15428 2/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ ABCC3 O15438 1/20 0.45
▸ ABCC4 O15439 1/20 0.45
▸ USP2 O75604 1/20 0.45
▸ SLCO2B1 O94956 1/20 0.45
▸ CA1 P00915 1/20 0.45
▸ CA2 P00918 1/20 0.45
▸ MMP1 P03956 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salazosulfadimidine SCHEMBL150333 0.84 AMY1A (0.63) AMY1AGAAKDRLMNATSHR
Salazosulfadimidine SCHEMBL31424085 0.84 AMY1A (0.63) AMY1AGAAKDRLMNATSHR
SCHEMBL10834904 0.74 AMY1A (0.61) AMY1AGAAKDRLMNATSHR
SCHEMBL10834896 0.74 AMY1A (0.61) AMY1AGAAKDRLMNATSHR
SCHEMBL14524469 0.73 GAA (0.64) AMY1AGAAKDRLMNATSHR
SCHEMBL17011237 0.73 GAA (0.64) AMY1AGAAKDRLMNATSHR
SCHEMBL10834633 0.73 AMY1A (0.60) AMY1AGAAKDRLMNATSHR
SCHEMBL10834640 0.73 AMY1A (0.60) AMY1AGAAKDRLMNATSHR
SCHEMBL13060910 0.71 GAA (0.61) AMY1AGAAKDRLMNATSHR
SCHEMBL11743625 0.71 PTGS1 (0.42) GAALMNATSHRALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 — — EP disclosed
CN-119580057-A InSAR-based mining area sedimentation funnel identification method, medium and device 中国地质大学(武汉) 2025-03-07 — — CN disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 — — US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 — — US disclosed
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2023-04-20 — — US disclosed
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels ASCENDIS PHARMA A/S (DE) 2023-01-24 — — US disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 — — EP disclosed
CN-113999188-A Cyperazine hapten and artificial antigen as well as preparation method and application thereof 中国农业大学 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels PLG, PHYKPL, PLOD3 AMY1A 3193/4885GAA 156/4885KDR 143/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 AMY1A 940/4885GAA 12/4885KDR 2030/4885
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels PLG, PHYKPL, PLOD3 AMY1A 3193/4885GAA 156/4885KDR 143/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 AMY1A 940/4885GAA 12/4885KDR 2030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback