SCHEMBL29373528

SCHEMBL29373528

C[C@H](NC(=O)CN)C(=O)NCC(=O)N1C[C@H](O)C[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ VHL P40337 2/20 0.52
▸ OPRM1 P35372 2/20 0.42
▸ OPRD1 P41143 2/20 0.42
▸ CALCRL Q16602 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16925966 1.00 VHL (0.52) VHLOPRM1OPRD1CALCRL
SCHEMBL19381670 1.00 VHL (0.52) VHLOPRM1OPRD1CALCRL
SCHEMBL16925967 0.96 VHL (0.49) VHLOPRM1OPRD1
SCHEMBL19381804 0.94 VHL (0.51) VHLOPRM1OPRD1
SCHEMBL16925995 0.89 VHL (0.46) VHLOPRM1OPRD1
SCHEMBL19381684 0.88 VHL (0.48) VHLOPRM1OPRD1CALCRL
SCHEMBL16925994 0.87 VHL (0.44) VHLOPRM1OPRD1
SCHEMBL16925974 0.85 VHL (0.44) VHLOPRM1OPRD1
SCHEMBL16925968 0.83 VHL (0.44) VHLOPRM1OPRD1CALCRL
SCHEMBL16925996 0.81 VHL (0.47) VHLOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739309-A1 DANEGAPTIDE FOR USE IN TREATING SYNUCLEINOPATHIES Cambridge Enterprise Limited (GB) 2026-05-13 — — EP disclosed
US-20260091017-A1 TREATMENTS FOR INFLAMMATION AUCKLAND UNISERVICES LTD (NZ) 2026-04-02 — — US disclosed
EP-4452260-B1 GAP JUNCTION MODULATORS AND THEIR USE FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION BREYE THERAPEUTICS APS (DK) 2026-01-28 — — EP disclosed
EP-4677087-A1 NOVEL TREATMENTS FOR OCULAR DISORDERS Glaukos Corporation (US) 2026-01-14 — — EP disclosed
US-20250352508-A1 PREVENTION AND TREATMENT OF POST-ACUTE INFECTION SYNDROMES INFLAMMX THERAPEUTICS INC (US) 2025-11-20 — — US disclosed
US-20250221936-A1 ENGINEERED HEMICHANNELS, ENGINEERED VESICLES, AND USES THEREOF VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2025-07-10 — — US disclosed
US-20250136987-A1 CHANNEL MODULATORS INFLAMMX THERAPEUTICS, INC. 2025-05-01 — — US disclosed
US-20250127851-A1 CYTOKINE MODULATION INFLAMMX THERAPEUTICS, INC. 2025-04-24 — — US disclosed
US-20250018002-A1 Gap Junction Modulators and Their Use for the Treatment of Age-Related Macular Degeneration BREYE THERAPEUTICS APS (DK) 2025-01-16 — — US disclosed
EP-4491184-A2 CHANNEL MODULATORS Auckland Uniservices Limited (NZ) 2025-01-15 — — EP disclosed
EP-3082768-B1 LIPOSOMAL MITIGATION OF DRUG-INDUCED INHIBITION OF THE CARDIAC IKR CHANNEL SIGNPATH PHARMA INC (US) 2023-02-22 — — EP disclosed
US-20220288163-A1 CYTOKINE MODULATION INFLAMMX THERAPEUTICS, INC. 2022-09-15 — — US disclosed
WO-2022171525-A1 DANEGAPTIDE FOR USE IN THE TREATMENT OR PREVENTION OF A KIDNEY DISEASE CIANA THERAPEUTICS APS (DK) 2022-08-18 — — WO disclosed
US-11401516-B2 Channel modulators AUCKLAND UNISERVICES LIMITED (NZ) 2022-08-02 — — US disclosed
US-11344603-B2 Cytokine modulation AUCKLAND UNISERVICES LIMITED (NZ) 2022-05-31 — — US disclosed
CN-114524885-A Auricularia auricula polysaccharide and application thereof 吉林农业大学 2022-05-24 — — CN disclosed
US-11324799-B2 Gap junction intercellular communication modulators and their use for the treatment of diabetic eye disease ZEALAND PHARMA A/S (DK) 2022-05-10 — — US disclosed
EP-3958886-A1 COMPOSITIONS AND METHODS FOR PROTECTING EPITHELIAL AND BARRIER INTEGRITY Ocunexus Therapeutics, Inc. (US) 2022-03-02 — — EP disclosed
CN-114010788-A Channel modulators 奥克兰联合服务有限公司 2022-02-08 — — CN disclosed
CN-114025786-A Compositions and methods for protecting epithelial and barrier integrity 欧耐柯萨斯医疗有限公司 2022-02-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091017-A1 TREATMENTS FOR INFLAMMATION P2RX7, NLRP3, PYCARD VHL 2374/4885OPRM1 3404/4885OPRD1 3942/4885
US-20250352508-A1 PREVENTION AND TREATMENT OF POST-ACUTE INFECTION SYNDROMES NLRP3, GJA1, PYCARD VHL 1659/4885OPRM1 3099/4885OPRD1 3363/4885
US-20250018002-A1 Gap Junction Modulators and Their Use for the Treatment of Age-Related Macular Degeneration GJA1, GJB2, VEGFA VHL 3016/4885OPRM1 2599/4885OPRD1 2679/4885
US-20250127851-A1 CYTOKINE MODULATION TNF, IL2, IL1B VHL 423/4885OPRM1 1795/4885OPRD1 1860/4885
US-20220288163-A1 CYTOKINE MODULATION TNF, IL2, IL1B VHL 423/4885OPRM1 1795/4885OPRD1 1860/4885
US-11401516-B2 Channel modulators GJB2, GJA1, P2RX2 VHL 809/4885OPRM1 655/4885OPRD1 1119/4885
US-11344603-B2 Cytokine modulation TNF, IL2, IL1B VHL 423/4885OPRM1 1795/4885OPRD1 1860/4885
US-20250136987-A1 CHANNEL MODULATORS GJB2, GJA1, P2RX2 VHL 809/4885OPRM1 655/4885OPRD1 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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