SCHEMBL29376536

SCHEMBL29376536

C=CCOC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 2/20 0.51
▸ TP53 P04637 2/20 0.51
▸ TLR2 O60603 2/20 0.51
▸ CASP3 P42574 2/20 0.48
▸ MDM2 Q00987 5/20 0.48
▸ CASP1 P29466 2/20 0.47
▸ TNF P01375 1/20 0.47
▸ SLC17A5 Q9NRA2 1/20 0.45
▸ KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29407853 1.00 MDM4 (0.51) MDM4TP53TLR2CASP3MDM2
SCHEMBL178741 1.00 MDM4 (0.51) MDM4TP53TLR2CASP3MDM2
SCHEMBL119481 1.00 MDM4 (0.51) MDM4TP53TLR2CASP3MDM2
SCHEMBL30055069 1.00 MDM4 (0.51) MDM4TP53TLR2CASP3MDM2
SCHEMBL25358998 0.94 MDM2 (0.51) MDM4TP53TLR2CASP3MDM2
SCHEMBL31398353 0.94 MDM2 (0.51) MDM4TP53TLR2CASP3MDM2
SCHEMBL31398346 0.94 MDM2 (0.51) MDM4TP53TLR2CASP3MDM2
SCHEMBL31689003 0.93 MDM2 (0.50) MDM4TP53TLR2CASP3MDM2
SCHEMBL29398655 0.92 TLR2 (0.48) MDM4TP53TLR2CASP3MDM2
SCHEMBL14417867 0.91 CASP3 (0.46) MDM4TP53TLR2CASP3MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118403181-A Novel multifunctional nano-drug carrier material and preparation method and application thereof 浙江工业大学 2024-07-30 — — CN claimed
CN-118324868-A Process for the preparation of desmopressin EP impurities E and F 梯尔希(南京)药物研发有限公司 2024-07-12 — — CN claimed
CN-115043901-B Dopaminization modified glutamine polypeptide, antibody thereof and application thereof 济宁医学院附属医院 2023-08-29 — — CN claimed
CN-115043901-A Dopamine modified glutamine polypeptide and antibody and application thereof 济宁医学院附属医院 2022-09-13 — — CN claimed
CN-113150075-B Cyclic poly-arginine cell-penetrating peptide molecule and synthesis method and application thereof 合肥工业大学 2022-07-26 — — CN claimed
EP-4741423-A2 ANTIBODY-DRUG CONJUGATES AND THEIR USES Mablink Bioscience (FR) 2026-05-13 — — EP disclosed
CN-122011117-A Cyclic peptide for resisting ultraviolet injury and application thereof in cosmetics 深圳肽盛渼生物科技有限公司 2026-05-12 — — CN disclosed
EP-4729529-A1 PREPARATION OF PEPTIDE INHIBITOR OF INTERLEUKIN-23 RECEPTOR AND USE THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2026-04-22 — — EP disclosed
US-12569536-B2 Macrocyclic peptides for targeted inhibition of autophagy BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-03-10 — — US disclosed
EP-4702986-A1 POLYPEPTIDE AND USE THEREOF Biocells (Beijing) Biotech Co., Ltd. (CN) 2026-03-04 — — EP disclosed
EP-4225772-B1 CYCLIC APELIN RECEPTOR AGONISTS NXERA PHARMA UK LTD (GB) 2026-02-25 — — EP disclosed
US-12551535-B2 Peptide pharmaceuticals for insulin resistance MEDERIS DIABETES, LLC (US) 2026-02-17 — — US disclosed
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound FUJIFILM CORPORATION (JP) 2022-05-03 — — US disclosed
US-20220119445-A1 SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF NATIONAL SCIENCE FOUNDATION 2022-04-21 — — US disclosed
US-20220096594-A1 MACROCYCLIC PEPTIDES FOR TARGETED INHIBITION OF AUTOPHAGY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-03-31 — — US disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 — — EP disclosed
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy PALATIN TECHNOLOGIES, INC. (US) 2022-03-29 — — US disclosed
US-20220088146-A1 Melanocortin Receptor-Specific Peptide Formulations and Methods for Gastrointestinal Tract-Specific Delivery PALATIN TECHNOLOGIES INC (US) 2022-03-24 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
US-20220041656-A1 NOVEL COMPOUND AND ANGIOGENIC AGENT COMPRISING SAME HIPEP LABORATORIES (JP) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041656-A1 NOVEL COMPOUND AND ANGIOGENIC AGENT COMPRISING SAME VEGFA, FLT1, FLT4 MDM4 4766/4885TP53 3939/4885TLR2 1629/4885
US-12569536-B2 Macrocyclic peptides for targeted inhibition of autophagy ATG7, SQSTM1, VIP MDM4 3017/4885TP53 415/4885TLR2 1741/4885
US-12551535-B2 Peptide pharmaceuticals for insulin resistance IAPP, GLP1R, INSR MDM4 2645/4885TP53 3467/4885TLR2 550/4885
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy MC3R, MC1R, MC2R MDM4 4380/4885TP53 3497/4885TLR2 502/4885
US-20220088146-A1 Melanocortin Receptor-Specific Peptide Formulations and Methods for Gastrointestinal Tract-Specific Delivery MC3R, GIPR, MC1R MDM4 4773/4885TP53 3820/4885TLR2 905/4885
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound VIP, NPPA, NGLY1 MDM4 4154/4885TP53 1409/4885TLR2 3116/4885
US-20220119445-A1 SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF VIP, PTMS, IAPP MDM4 1657/4885TP53 1578/4885TLR2 4126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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