Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Diethylene Glycol Monoethyl Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 4/20 | 0.65 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL31282314 | 1.00 | ALDH1A1 (0.82) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL5187865 | 1.00 | ALDH1A1 (0.82) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL10628039 | 0.97 | ALDH1A1 (0.88) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL15659 | 0.97 | ALDH1A1 (0.88) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL11137235 | 0.97 | ALDH1A1 (0.88) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL16399 | 0.97 | — | — | |
| SCHEMBL18418083 | 0.97 | ALDH1A1 (0.88) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL2743512 | 0.97 | ALDH1A1 (0.88) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| Triethylene Glycol SCHEMBL21647314 | 0.97 | ALDH1A1 (0.88) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL3268631 | 0.97 | ALDH1A1 (0.88) | ALDH1A1MEN1KMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795141-B1 | SOLID SOLUTION COMPOSITIONS | INFIRST HEALTHCARE LTD (GB) | 2025-07-30 | — | — | EP | disclosed |
| US-20240277613-A1 | Solid Solution Compositions and Use in Chronic Inflammation | INFIRST HEALTHCARE LIMITED (GB) | 2024-08-22 | — | — | US | disclosed |
| US-20240207408-A1 | Solid Solution Compositions and Use in Severe Pain | INFIRST HEALTHCARE LIMITED (GB) | 2024-06-27 | — | — | US | disclosed |
| US-11992555-B2 | Solid solution compositions and use in chronic inflammation | INFIRST HEALTHCARE LIMITED (GB) | 2024-05-28 | — | — | US | disclosed |
| US-11918654-B2 | Solid solution compositions and use in severe pain | INFIRST HEALTHCARE LIMITED (GB) | 2024-03-05 | — | — | US | disclosed |
| US-11844773-B2 | Solid solution compositions and use in chronic inflammation | INFIRST HEALTHCARE LIMITED (GB) | 2023-12-19 | — | — | US | disclosed |
| US-11826428-B2 | Solid solution compositions comprising cannabidiols | INFIRST HEALTHCARE LIMITED (GB) | 2023-11-28 | — | — | US | disclosed |
| US-20220118091-A1 | Solid Solution Compositions and Use in Severe Pain | INFIRST HEALTHCARE LIMITED (GB) | 2022-04-21 | — | — | US | disclosed |
| US-20220096637-A1 | Solid Solution Compositions and Use in Cardiovascular Disease | INFIRST HEALTHCARE LIMITED (GB) | 2022-03-31 | — | — | US | disclosed |
| CN-109549927-B | Solid solution compositions and their use in cardiovascular disease | 因佛斯特医疗有限公司 | 2022-03-29 | — | — | CN | disclosed |
| US-20220040102-A1 | Solid Solution Compositions and Use in Chronic Inflammation | INFIRST HEALTHCARE LIMITED (GB) | 2022-02-10 | — | — | US | disclosed |