SCHEMBL29379999

SCHEMBL29379999

CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@H]2CSSC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC2=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)[C@@H](C)CC

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 1/20 0.55
KCNMB4 Q86W47 1/20 0.55
RXFP4 Q8TDU9 5/20 0.50
RXFP3 Q9NSD7 5/20 0.50
SSTR2 P30874 4/20 0.49
SSTR5 P35346 4/20 0.49
RXFP1 Q9HBX9 1/20 0.48
TET2 Q6N021 1/20 0.48
TET1 Q8NFU7 1/20 0.48
SSTR4 P31391 2/20 0.47
PCSK9 Q8NBP7 1/20 0.47
TP53 P04637 4/20 0.46
MDM2 Q00987 4/20 0.46
SSTR3 P32745 1/20 0.46
IL23R Q5VWK5 1/20 0.45
PLAU P00749 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Endothelin SCHEMBL29352622 0.97 KCNMA1 (0.53) KCNMA1KCNMB4RXFP4RXFP3SSTR2
SCHEMBL26929028 0.95 KCNMA1 (0.55) KCNMA1KCNMB4RXFP4RXFP3SSTR2
SCHEMBL29403556 0.95 KCNMA1 (0.55) KCNMA1KCNMB4RXFP4RXFP3SSTR2
Endothelin SCHEMBL29403065 0.91 RXFP1 (0.55) KCNMA1KCNMB4RXFP4RXFP3RXFP1
Endothelin SCHEMBL21644373 0.91 RXFP1 (0.55) KCNMA1KCNMB4RXFP4RXFP3RXFP1
SCHEMBL29484633 0.90 KCNMA1 (0.55) KCNMA1KCNMB4RXFP4RXFP3RXFP1
SCHEMBL29661263 0.89 KCNMA1 (0.55) KCNMA1KCNMB4SSTR2SSTR5RXFP1
SCHEMBL29921568 0.87 KCNMA1 (0.54) KCNMA1KCNMB4RXFP4RXFP3RXFP1
SCHEMBL21412610 0.81 IL23R (0.58) KCNMA1KCNMB4RXFP3SSTR2SSTR5
SCHEMBL21412615 0.81 IL23R (0.58) KCNMA1KCNMB4RXFP3SSTR2SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460177-B2 Composition for promoting efficiency of somatic cell replication SEOUL NATIONAL UNIVERSITY HOSPITAL (KR) 2025-11-04 US claimed
WO-2024232849-A1 A PHARMACEUTICAL COMPOSITION FOR INCREASING MELANIN SYNTHESIS IN HAIR FOLLICLES IFL PHARMA ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) 2024-11-14 WO claimed
US-11450431-B2 Method to identify optimum coronary artery disease treatment SIEMENS HEALTHCARE GMBH (DE) 2022-09-20 US claimed
US-20260109760-A1 NEUTRALIZING ANTIBODIES TO HUMAN ENDOTHELIN FATHER FLANAGANS BOYS HOME DOING BUSINESS AS BOYS TOWN NATIONAL RES HOSPITAL (US) 2026-04-23 US disclosed
EP-4715043-A1 METHOD FOR PRODUCING NEURAL CREST CELLS Kyoto University (JP) 2026-03-25 EP disclosed
US-12577300-B2 Neutralizing antibodies to human endothelin Father Flanagan's Boys' Home Business (US) 2026-03-17 US disclosed
US-20260060221-A1 METHOD FOR PRODUCING NONHUMAN PRIMATE ANIMAL MODEL OF CEREBRAL INFARCTION AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CEREBRAL INFARCTION ASTELLAS PHARMA INC. (JP) 2026-03-05 US disclosed
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) UNIV LELAND STANFORD JUNIOR (US) 2026-02-19 US disclosed
EP-4673949-A1 A METHOD FOR DETERMINING A STAGE OF AN EPIGENETIC PROPERTY OF AN EPIDERMIS Mitra Bio Limited (GB) 2026-01-07 EP disclosed
EP-4149556-B1 PEG LIPIDOID COMPOUNDS TRANSLATE BIO INC (US) 2026-01-07 EP disclosed
US-12516083-B2 Nucleophilic catalysts for oxime linkage TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-01-06 US disclosed
EP-2849795-B1 METHODS FOR PREPARING THERAPEUTIC PROTEIN-POLYMER CONJUGATES TAKEDA PHARMACEUTICALS CO (JP) 2022-04-06 EP disclosed
CN-106459160-B ASX-specific protein ligases 南洋理工大学 2022-03-29 CN disclosed
US-11278748-B2 Endothelin-converting enzyme inhibitor KAO CORPORATION (JP) 2022-03-22 US disclosed
EP-3966321-A1 ASX-SPECIFIC PROTEIN LIGASES AND USES THEREOF Nanyang Technological University (SG) 2022-03-16 EP disclosed
US-20220073944-A1 MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF TRANSLATE BIO, INC. 2022-03-10 US disclosed
US-20220071905-A1 PEG LIPIDOID COMPOUNDS TRANSLATE BIO, INC. 2022-03-10 US disclosed
CN-114085810-A Preparation method of similar mesenchymal stem cells and similar mesenchymal stem cells prepared by same 株式会社未来细胞生物 2022-02-25 CN disclosed
CN-112245363-B Salvia miltiorrhiza whitening and freckle removing mask 山东农业大学 2022-02-11 CN disclosed
CN-109846762-B Composition with whitening effect and preparation method and application thereof 上海珈凯生物科技有限公司 2022-02-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060221-A1 METHOD FOR PRODUCING NONHUMAN PRIMATE ANIMAL MODEL OF CEREBRAL INFARCTION AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CEREBRAL INFARCTION FABP7, NES, VEGFA KCNMA1 3134/4885KCNMB4 3272/4885RXFP4 2585/4885
US-20260109760-A1 NEUTRALIZING ANTIBODIES TO HUMAN ENDOTHELIN ETV1, CDR2, IGLV6-57 KCNMA1 1850/4885KCNMB4 2497/4885RXFP4 2416/4885
US-20220073944-A1 MULTIMERIC CODING NUCLEIC ACID AND USES THEREOF NSUN3, TRDMT1, NSUN2 KCNMA1 1926/4885KCNMB4 2675/4885RXFP4 4138/4885
US-12577300-B2 Neutralizing antibodies to human endothelin IGLV6-57, ETV1, VEGFA KCNMA1 1666/4885KCNMB4 1594/4885RXFP4 1751/4885
US-20220071905-A1 PEG LIPIDOID COMPOUNDS HDLBP, LIPG, ABCB4 KCNMA1 4494/4885KCNMB4 4266/4885RXFP4 4470/4885
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) ADAR, ZFR, SLIRP KCNMA1 4708/4885KCNMB4 4633/4885RXFP4 964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.