SCHEMBL29384682

SCHEMBL29384682

CC(=O)c1ccc(O)cc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 4/20 0.56
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.47
CES2 O00748 1/20 0.46
CA12 O43570 4/20 0.45
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
CA7 P43166 4/20 0.45
CA9 Q16790 4/20 0.45
CA14 Q9ULX7 4/20 0.45
TSHR P16473 1/20 0.45
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
S1PR4 O95977 1/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
MIF P14174 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96129 1.00 HSD17B1 (0.56) HSD17B1ALDH1A1CYP3A4HPGDMAPK1
SCHEMBL10370024 0.84 CES2 (0.60) HSD17B1ALDH1A1CYP3A4CES2CA12
SCHEMBL764844 0.84 SMN1; SMN2 (0.50) HSD17B1ALDH1A1CYP3A4HPGDCES2
SCHEMBL39526 0.82 CA12 (0.61) HSD17B1ALDH1A1CYP3A4HPGDCES2
SCHEMBL9216747 0.82 HSD17B1 (0.47) HSD17B1ALDH1A1CYP3A4HPGDMAPK1
SCHEMBL16520525 0.81 ALDH1A1 (0.55) HSD17B1ALDH1A1CYP3A4HPGDMAPK1
SCHEMBL14900218 0.80 HSD17B1 (0.46) HSD17B1ALDH1A1CYP3A4HPGDCES2
SCHEMBL27500611 0.80 CA12 (0.59) HSD17B1ALDH1A1CYP3A4HPGDCES2
SCHEMBL5952602 0.80 MKNK1 (0.47) HSD17B1ALDH1A1CES2CA12CA1
SCHEMBL27659033 0.80 CA12 (0.59) HSD17B1ALDH1A1CYP3A4HPGDCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658656-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
EP-4541364-A1 PEACH BLOSSOM FERMENTATION LIQUID FOR IMPROVING CONSTIPATION, AND PREPARATION METHOD AND USE THEREOF South China Agricultural University (CN) 2025-04-23 EP disclosed
CN-119677514-A Estrogenic compounds and methods of use 益特瑞恩公司 2025-03-21 CN disclosed
CN-119212727-A Targeted bifunctional degradants 耶鲁大学 2024-12-27 CN disclosed
WO-2024160276-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 WO disclosed
CN-111170991-B Antiproliferative compounds and methods of synthesis thereof 细胞基因公司 2023-10-31 CN disclosed
CN-115315272-A Targeting difunctional degradation agent 耶鲁大学 2022-11-08 CN disclosed
US-20220039421-A1 BEVERAGE COMPOSITIONS COMPRISING WATER-SOLUBLE PALM FRUIT BIOACTIVE COMPLEX/OIL PALM PHENOLICS AND PALM FRUIT JUICE PHENOLAEIS MEXICO SAPI DE CV (MX) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220039421-A1 BEVERAGE COMPOSITIONS COMPRISING WATER-SOLUBLE PALM FRUIT BIOACTIVE COMPLEX/OIL PALM PHENOLICS AND PALM FRUIT JUICE SFRP1, OSBP, LIPC HSD17B1 3326/4885ALDH1A1 1244/4885CYP3A4 3132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.