SCHEMBL29385016

SCHEMBL29385016

CN1CCN(C(=O)c2nc3ccc(Cl)cc3[nH]2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 18/20 1.00
HRH3 Q9Y5N1 2/20 1.00
ALOX15 P16050 1/20 0.87
HRH1 P35367 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16939347 1.00 HRH4 (1.00) HRH4HRH3ALOX15HRH1
Maleic Acid SCHEMBL29769889 0.93 ALOX15 (1.00) HRH4HRH3ALOX15HRH1
SCHEMBL602043 0.90 HRH4 (0.81) HRH4HRH3ALOX15HRH1
SCHEMBL603185 0.84 HRH4 (0.73) HRH4HRH3ALOX15HRH1
Maleic Acid SCHEMBL602941 0.83 ALOX15 (0.84) HRH4HRH3ALOX15HRH1
Maleic Acid SCHEMBL29404707 0.83 ALOX15 (0.84) HRH4HRH3ALOX15HRH1
Fumaric Acid SCHEMBL602943 0.83 ALOX15 (0.84) HRH4HRH3ALOX15HRH1
Maleic Acid SCHEMBL20162482 0.83 ALOX15 (0.84) HRH4HRH3ALOX15HRH1
Jnj-7777120 SCHEMBL18486196 0.83 HRH4 (0.80) HRH4HRH3ALOX15HRH1
SCHEMBL13914874 0.81 HRH4 (1.00) HRH4HRH3ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
CN-115803088-B Cyclobenzaprine treatment of sexual dysfunction 通尼克斯医药控股公司 2025-03-21 CN claimed
US-20240415789-A1 CYCLOBENZAPRINE FOR TREATMENT OR PREVENTION OF SEXUAL DYSFUNCTION ASSOCIATED WITH MENTAL HEALTH CONDITIONS IN FEMALE PATIENTS TONIX PHARMA LIMITED (IE) 2024-12-19 US claimed
EP-4412602-A1 CYCLOBENZAPRINE FOR TREATMENT OR PREVENTION OF SEXUAL DYSFUNCTION ASSOCIATED WITH MENTAL HEALTH CONDITIONS IN FEMALE PATIENTS Tonix Pharmaceuticals Holding Corp. (US) 2024-08-14 EP claimed
EP-4294446-A1 SYSTEMS, DEVICES, AND FORMULATIONS FOR TIME-PHASED HISTAMINE DELIVERY Agonex Biopharmaceuticals, Inc. (US) 2023-12-27 EP claimed
US-20230390215-A1 SYSTEMS, DEVICES, AND FORMULATIONS FOR TIME-PHASED HISTAMINE DELIVERY AGONEX BIOPHARMACEUTICALS, INC. 2023-12-07 US claimed
WO-2023059728-A1 CYCLOBENZAPRINE FOR TREATMENT OR PREVENTION OF SEXUAL DYSFUNCTION ASSOCIATED WITH MENTAL HEALTH CONDITIONS IN FEMALE PATIENTS TONIX PHARMACEUTICALS HOLDING CORP. (US) 2023-04-13 WO claimed
CN-115803088-A Cyclobenzaprine treatment of sexual dysfunction 通尼克斯医药控股公司 2023-03-14 CN claimed
EP-4132648-A1 CYCLOBENZAPRINE TREATMENT FOR SEXUAL DYSFUNCTION Tonix Pharmaceuticals Holding Corp. (US) 2023-02-15 EP claimed
WO-2022178120-A1 SYSTEMS, DEVICES, AND FORMULATIONS FOR TIME-PHASED HISTAMINE DELIVERY AGONEX BIOPHARMACEUTICALS, INC. (US) 2022-08-25 WO claimed
US-12637452-B2 Crystalline forms of a substituted imidazopyridine compound and use thereof as P2X3 modulator GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) 2026-05-26 US disclosed
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO disclosed
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS MODEL MEDICINES INC (US) 2026-05-07 US disclosed
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES MODEL MEDICINES INC (US) 2026-04-16 US disclosed
US-20260097103-A1 FUNCTIONALIZED BIOCATALYTICAL COMPOSITIONS PERSEO PHARMA AG (CH) 2026-04-09 US disclosed
US-11383084-B2 Treatment of dermatological conditions via neuromodulation PALO ALTO INVESTORS (US) 2022-07-12 US disclosed
EP-3973961-A1 USE OF HYDROXYZINE AND ANTIHISTAMINE ANALOGS FOR TREATING THE COVID-19 DISEASE ASSISTANCE PUBLIQUE, HOPITAUX DE PARIS (FR) 2022-03-30 EP disclosed
US-11274158-B2 Methods and compositions for treating inflammatory or autoimmune diseases or conditions using calcitonin receptor activators FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2022-03-15 US disclosed
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2022-02-24 US disclosed
US-20220040300-A1 METHOD OF FILLING A CONTAINER WITH NO HEADSPACE HONG KONG KING-FRIEND INDUSTRIAL COMPANY LTD. (CN) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220054499-A1 SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION MKI67, MYLK2, MYH2 HRH4 4481/4885HRH3 3968/4885ALOX15 3805/4885
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES ESR1, VDR, POLL HRH4 4405/4885HRH3 4233/4885ALOX15 1858/4885
US-20260097103-A1 FUNCTIONALIZED BIOCATALYTICAL COMPOSITIONS CTRL, PREP, ANPEP HRH4 4151/4885HRH3 3870/4885ALOX15 2062/4885
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS SARS1, NSUN2, NSUN3 HRH4 4319/4885HRH3 4397/4885ALOX15 2426/4885
US-12637452-B2 Crystalline forms of a substituted imidazopyridine compound and use thereof as P2X3 modulator P2RX3, P2RX2, P2RX4 HRH4 219/4885HRH3 151/4885ALOX15 4141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.