Bezitramide

Bezitramide

SCHEMBL29387545

CCC(=O)n1c(=O)n(C2CCN(CCC(C#N)(c3ccccc3)c3ccccc3)CC2)c2ccccc21

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.55
KCNA3 P22001 10/20 0.54
RAB9A P51151 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
OPRL1 P41146 1/20 0.47
CCR3 P51677 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bezitramide SCHEMBL25733 1.00 OPRM1 (0.55) OPRM1KCNA3RAB9ANPSR1OPRL1
Bezitramide SCHEMBL28086670 0.83 OPRM1 (0.52) OPRM1KCNA3RAB9ANPSR1OPRL1
Bezitramide SCHEMBL466257 0.81 OPRM1 (0.57) OPRM1KCNA3OPRL1
Bezitramide SCHEMBL28086184 0.79 SIGMAR1 (0.52) OPRM1NPSR1
SCHEMBL2573257 0.71 OPRM1 (1.00) OPRM1KCNA3OPRL1
Hydrochloric Acid SCHEMBL11625263 0.71 KCNA3 (0.97) OPRM1KCNA3RAB9ANPSR1CCR3
SCHEMBL30659491 0.70 KCNA3 (0.75) OPRM1KCNA3RAB9ANPSR1CCR3
SCHEMBL904853 0.70 CCR3 (0.55) KCNA3CCR3
SCHEMBL3604592 0.69 CACNA1G (0.58) OPRM1OPRL1
SCHEMBL5858628 0.69 DRD2 (0.61) OPRM1KCNA3RAB9ANPSR1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3682872-B1 LIQUISOFT CAPSULES PATHEON SOFTGELS INC (US) 2024-01-03 EP claimed
EP-3064199-B1 ABUSE-DETERRENT TRANSDERMAL FORMULATIONS OF OPIATE AGONISTS AND AGONIST-ANTAGONISTS BUZZZ PHARMACEUTICALS LTD (IE) 2023-12-20 EP claimed
EP-3313407-B1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2023-07-19 EP claimed
EP-3385252-B1 CANNABINOID RECEPTOR MODULATORS ARENA PHARM INC (US) 2022-09-21 EP claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
US-20250302768-A1 NANOPARTICLE DOPED POLYETHYLENE GLYCOL BASED GELS AND MEDICAL DEVICES FOR DRUG DELIVERY THE GENERAL HOSPITAL CORPORATION 2025-10-02 US disclosed
CN-119212681-A Method for preparing 3-D printed pharmaceutical products 百时美施贵宝公司 2024-12-27 CN disclosed
WO-2023220717-A2 NANOPARTICLE DOPED POLYETHYLENE GLYCOL BASED GELS AND MEDICAL DEVICES FOR DRUG DELIVERY THE GENERAL HOSPITAL CORPORATION (US) 2023-11-16 WO disclosed
US-20230293695-A1 Tamper Resistant Pharmaceutical Formulations PURDUE PHARMA LP (US) 2023-09-21 US disclosed
EP-1765303-B2 ORAL TABLET SAFEGUARDED AGAINST ABUSE GRUENENTHAL GMBH (DE) 2022-11-23 EP disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed