SCHEMBL29388908

SCHEMBL29388908

NC1C=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ TK1 P04183 3/20 0.46
▸ ADRB1 P08588 1/20 0.46
▸ DNMT1 P26358 1/20 0.46
▸ ALOX12 P18054 1/20 0.44
▸ ADRA1A P35348 1/20 0.44
▸ TK2 O00142 1/20 0.43
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ PMP22 Q01453 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16378861 1.00 LMNA (0.49) LMNASMN1; SMN2TK1ADRB1DNMT1
SCHEMBL22765896 0.83 TYMS (0.50) —
SCHEMBL19120634 0.79 TK1 (0.50) LMNASMN1; SMN2TK1ADRB1DNMT1
SCHEMBL6364684 0.79 LMNA (0.44) LMNASMN1; SMN2TK1ADRB1DNMT1
SCHEMBL2209009 0.79 ADRB1 (0.47) LMNASMN1; SMN2TK1ADRB1DNMT1
SCHEMBL19107434 0.79 TK1 (0.50) LMNASMN1; SMN2TK1ADRB1DNMT1
SCHEMBL22183560 0.78 TK1 (0.44) LMNASMN1; SMN2TK1ADRB1DNMT1
SCHEMBL4214653 0.78 LMNA (0.49) LMNASMN1; SMN2TK1ADRB1DNMT1
SCHEMBL4214655 0.78 LMNA (0.49) LMNASMN1; SMN2TK1ADRB1DNMT1
SCHEMBL25492408 0.78 TK1 (0.44) LMNASMN1; SMN2TK1ADRB1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS MODERNATX, INC. (US) 2026-05-28 — — US disclosed
EP-4727914-A1 COMPOUNDS AND COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2026-04-22 — — EP disclosed
US-12595226-B2 Carbonate containing lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2026-04-07 — — US disclosed
EP-4687992-A1 LIPID-BASED NANOPARTICLE TARGETED AT ACTIVATED IMMUNE CELLS FOR THE EXPRESSION OF IMMUNE CELL INHIBITING MOLECULE AND USE THEREOF OSE IMMUNOTHERAPEUTICS (FR) 2026-02-11 — — EP disclosed
EP-4687991-A1 LIPID-BASED NANOPARTICLE TARGETED AT ACTIVATED IMMUNE CELLS FOR THE EXPRESSION OF IMMUNE CELL ENHANCING MOLECULE AND USE THEREOF OSE IMMUNOTHERAPEUTICS (FR) 2026-02-11 — — EP disclosed
EP-4683666-A1 PEG TARGETING COMPOUNDS FOR DELIVERY OF THERAPEUTICS ModernaTX, Inc. (US) 2026-01-28 — — EP disclosed
EP-4683667-A1 PEG TARGETING COMPOUNDS FOR DELIVERY OF THERAPEUTICS ModernaTX, Inc. (US) 2026-01-28 — — EP disclosed
EP-4683665-A1 PEG TARGETING COMPOUNDS FOR DELIVERY OF THERAPEUTICS ModernaTX, Inc. (US) 2026-01-28 — — EP disclosed
US-20260014281-A1 PEG TARGETING COMPOUNDS FOR DELIVERY OF THERAPEUTICS MODERNATX, INC. (US) 2026-01-15 — — US disclosed
US-20260014258-A1 PEG TARGETING COMPOUNDS FOR DELIVERY OF THERAPEUTICS MODERNATX, INC. (US) 2026-01-15 — — US disclosed
EP-4096644-A1 METHODS OF PREPARING LIPID NANOPARTICLES Modernatx, Inc. (US) 2022-12-07 — — EP disclosed
US-20220362372-A1 IMMUNOGENIC COMPOSITION AGAINST INFLUENZA PFIZER INC. 2022-11-17 — — US disclosed
WO-2022204288-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2022-09-29 — — WO disclosed
CN-115025247-A Composition for encapsulating thrombopoietin mRNA and application thereof 上海交通大学医学院 2022-09-09 — — CN disclosed
EP-4045647-A1 NOVEL RNA APTAMER INTERVENES ESTROGEN RECEPTOR INTERACTION WITH COACTIVATOR MED1 TO OVERCOME BREAST CANCER METASTASIS University of Cincinnati (US) 2022-08-24 — — EP disclosed
EP-4039811-A1 IMPROVED METHODS FOR PROCESSING DNA SUBSTRATES Integrated DNA Technologies, Inc. (US) 2022-08-10 — — EP disclosed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 — — WO disclosed
US-20220162672-A1 METHODS FOR MULTIPLEX PCR SWIFT BIOSCIENCES, INC. 2022-05-26 — — US disclosed
US-20220106259-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2022-04-07 — — US disclosed
WO-2022032154-A2 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM MODERNATX, INC. (US) 2022-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595226-B2 Carbonate containing lipid compounds and compositions for intracellular delivery of therapeutic agents LNPK, PCTP, PLTP LMNA 266/4885SMN1; SMN2 567/4885TK1 2571/4885
US-20260014258-A1 PEG TARGETING COMPOUNDS FOR DELIVERY OF THERAPEUTICS ASGR1, LDLR, LPAR6 LMNA 757/4885SMN1; SMN2 1622/4885TK1 1383/4885
US-20220362372-A1 IMMUNOGENIC COMPOSITION AGAINST INFLUENZA RNASEH1, HAVCR2, HNRNPH3 LMNA 772/4885SMN1; SMN2 2309/4885TK1 746/4885
US-20260014281-A1 PEG TARGETING COMPOUNDS FOR DELIVERY OF THERAPEUTICS ASGR1, LDLR, LPAR6 LMNA 691/4885SMN1; SMN2 1495/4885TK1 1376/4885
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS ELAVL1, IGF2BP2, FUS LMNA 754/4885SMN1; SMN2 75/4885TK1 4646/4885
US-20220106259-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PLTP, LNPK, PLIN3 LMNA 712/4885SMN1; SMN2 1663/4885TK1 422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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