Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 1.00 |
| ▸ | MET | P08581 | 19/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394339 | 0.90 | MET (1.00) | KCNH2MET | |
| SCHEMBL27924860 | 0.88 | MET (1.00) | KCNH2MET | |
| SCHEMBL19249224 | 0.71 | TDO2 (1.00) | MET | |
| SCHEMBL520396 | 0.69 | HTR7 (0.56) | — | |
| SCHEMBL20272696 | 0.67 | ALDH1A1 (0.57) | KCNH2MET | |
| SCHEMBL20445303 | 0.67 | ALDH1A1 (0.66) | — | |
| SCHEMBL6864351 | 0.66 | KDM4E (0.60) | — | |
| SCHEMBL27804767 | 0.66 | MET (0.61) | KCNH2MET | |
| SCHEMBL2485886 | 0.66 | SIRT6 (0.77) | — | |
| SCHEMBL28402916 | 0.62 | ALDH1A1 (0.56) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230398146-A1 | IMMUNE MODULATION OF MYELOID DERIVED SUPPRESSIVE CELL FUNCTION FOR CANCER TREATMENT | SURGE Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| CN-116322702-A | Immunomodulation of myeloid-derived suppressor cell function for cancer treatment | 萨吉治疗公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4196122-A1 | IMMUNE MODULATION OF MYELOID DERIVED SUPPRESSIVE CELL FUNCTION FOR CANCER TREATMENT | Surge Therapeutics, Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022040246-A1 | IMMUNE MODULATION OF MYELOID DERIVED SUPPRESSIVE CELL FUNCTION FOR CANCER TREATMENT | STIMIT CORPORATION (US) | 2022-02-24 | — | — | WO | disclosed |