SCHEMBL29400379

SCHEMBL29400379

Cc1ccccc1N=Nc1c(N)ccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 3/20 0.51
▸ TSHR P16473 2/20 0.51
▸ TP53 P04637 1/20 0.51
▸ CYP3A4 P08684 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ TDP1 Q9NUW8 1/20 0.51
▸ THRB P10828 1/20 0.50
▸ GFER P55789 1/20 0.48
▸ KMT2A Q03164 5/20 0.46
▸ SENP2 Q9HC62 4/20 0.46
▸ SENP1 Q9P0U3 4/20 0.46
▸ MAPT P10636 4/20 0.44
▸ L3MBTL1 Q9Y468 3/20 0.44
▸ NPC1 O15118 3/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ SUMO2 P61956 3/20 0.43
▸ SUMO1 P63165 3/20 0.43
▸ SENP7 Q9BQF6 3/20 0.43
▸ SENP3 Q9H4L4 3/20 0.43
▸ CCNE2 O96020 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1418053 1.00 MAPK1 (0.51) MAPK1TSHRTP53CYP3A4SMN1; SMN2
SCHEMBL4906400 1.00 MAPK1 (0.51) MAPK1TSHRTP53CYP3A4SMN1; SMN2
SCHEMBL17923171 0.85 THRB (0.71) MAPK1TSHRTP53CYP3A4SMN1; SMN2
SCHEMBL17923170 0.85 THRB (0.71) MAPK1TSHRTP53CYP3A4SMN1; SMN2
SCHEMBL7894499 0.85 SENP2 (0.57) MAPK1TSHRCYP3A4TDP1THRB
SCHEMBL8520460 0.85 SENP2 (0.57) MAPK1TSHRCYP3A4TDP1THRB
SCHEMBL29355974 0.81 THRB (0.74) MAPK1TSHRSMN1; SMN2TDP1THRB
SCHEMBL30776094 0.81 THRB (0.74) MAPK1TSHRSMN1; SMN2TDP1THRB
SCHEMBL2299642 0.81 THRB (0.74) MAPK1TSHRSMN1; SMN2TDP1THRB
SCHEMBL52228 0.81 THRB (0.74) MAPK1TSHRSMN1; SMN2TDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260090962-A1 SURFACE TREATED HYDROPHOBIC CELLULOSE MIYOSHI AMERICA INC (US) 2026-04-02 — — US disclosed
WO-2025004790-A1 TABLET TOPPANホールディングス株式会社 2025-01-02 — — WO disclosed
EP-3528769-B1 SOLID HAIR COLOURING COMPOSITION COSMETIC WARRIORS LTD (GB) 2024-10-23 — — EP disclosed
CN-113453906-B Ink for inkjet and printed material 凸版印刷株式会社 2023-07-07 — — CN disclosed
US-20220127157-A1 TITANATE CRYSTALS AND SURFACE TREATED TITANATE CRYSTALS MIYOSHI KASEI, INC. (JP) 2022-04-28 — — US disclosed
US-20220127158-A1 TITANATE CRYSTAL PARTICLE DISPERSIONS OTSUKA CHEMICAL CO., LTD. (JP) 2022-04-28 — — US disclosed
CN-114096919-A Method for producing photosensitive composition, paste-like photosensitive composition, method for producing electronic component, and device for determining mixing ratio of organic component in photosensitive composition, and computer program 株式会社则武 2022-02-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127158-A1 TITANATE CRYSTAL PARTICLE DISPERSIONS TYR, CUTA, TTN MAPK1 4096/4885TSHR 358/4885TP53 409/4885
US-20260090962-A1 SURFACE TREATED HYDROPHOBIC CELLULOSE CUTA, SMURF1, SMURF2 MAPK1 3127/4885TSHR 2737/4885TP53 189/4885
US-20220127157-A1 TITANATE CRYSTALS AND SURFACE TREATED TITANATE CRYSTALS TYR, CUTA, TTN MAPK1 4229/4885TSHR 316/4885TP53 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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