SCHEMBL29401545

SCHEMBL29401545

CC(C)(C)OC(=O)N[C@@H](Cc1cn(COCc2ccccc2)cn1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.56
PPARG P37231 2/20 0.52
ACE P12821 1/20 0.50
CTSS P25774 3/20 0.48
PTPN1 P18031 7/20 0.46
CDC25B P30305 4/20 0.46
PTPN2 P17706 3/20 0.46
CDC25A P30304 2/20 0.46
PTPN6 P29350 1/20 0.46
PTPN11 Q06124 1/20 0.46
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CTSK P43235 1/20 0.44
KLK7 P49862 2/20 0.44
KLK5 Q9Y337 1/20 0.44
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43
MAPK1 P28482 1/20 0.43
CPB2 Q96IY4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401820 1.00 PPARA (0.56) PPARAPPARGACECTSSPTPN1
SCHEMBL3429311 0.88 ACE (0.56) PPARAPPARGACECTSSPTPN1
SCHEMBL17642069 0.88 ACE (0.56) PPARAPPARGACECTSSPTPN1
SCHEMBL18468298 0.88 ITGB3 (0.48) PPARAPPARGCTSSCTSLCTSB
SCHEMBL6324267 0.86 ACE (0.52) PPARAPPARGACECTSSPTPN1
SCHEMBL12942569 0.83 CPB2 (0.49) ACEPTPN1CTSKITGB3ITGA2B
SCHEMBL5358340 0.82 MAPT (0.46) PPARAPPARGACECTSSCTSL
SCHEMBL13711132 0.82 PPARA (0.51) PPARAPPARGACECTSSPTPN1
SCHEMBL6329225 0.80 CPB2 (0.64) PPARAPPARGACEPTPN1ITGB3
SCHEMBL19508750 0.80 KLK5 (0.51) PPARAPPARGACECTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612441-B2 Polypeptide and therapeutic uses thereof VITALIXIR (BEIJING) CO., LTD (CN) 2026-04-28 US disclosed
CN-118679179-B Long-acting GLP-1 polypeptide compound, composition and application thereof 内蒙古博睿精创科技有限公司 2025-05-09 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
CN-113614102-B Novel polypeptides and therapeutic uses thereof 鸿绪生物医药科技(北京)有限公司 2024-08-13 CN disclosed
CN-118126124-A Bioactive polypeptide with QRRAD structure, composition and application thereof 深圳市肽金生物科技有限公司 2024-06-04 CN disclosed
US-20240067694-A1 SYNTHESIS OF TEDUGLUTIDE BIOCON LIMITED (IN) 2024-02-29 US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
EP-3524261-B1 EXENDIN FOR USE IN TREATING DIABETES AND REDUCING BODY WEIGHT AMYLIN PHARMACEUTICALS LLC (US) 2023-12-13 EP disclosed
US-20230263896-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF VITALIXIR (BEIJING) CO., LTD (CN) 2023-08-24 US disclosed
EP-4177263-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF Vitalixir (Beijing) Co., Ltd (CN) 2023-05-10 EP disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
US-20220127323-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USES THEREOF VITALIXIR (BEIJING) CO., LTD (CN) 2022-04-28 US disclosed
US-11285103-B2 Degradable hydrogel under physiological conditions HAN JIE (CN) 2022-03-29 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612441-B2 Polypeptide and therapeutic uses thereof VIP, GCG, GLS PPARA 3619/4885PPARG 1881/4885ACE 940/4885
US-20220127323-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USES THEREOF VIP, IAPP, LNPEP PPARA 3025/4885PPARG 4089/4885ACE 297/4885
US-11285103-B2 Degradable hydrogel under physiological conditions PTMS, TRHDE, PHYKPL PPARA 4036/4885PPARG 3417/4885ACE 2491/4885
US-20230263896-A1 NOVEL POLYPEPTIDE AND THERAPEUTIC USE THEREOF VIP, IAPP, LNPEP PPARA 2927/4885PPARG 3932/4885ACE 286/4885
US-20240067694-A1 SYNTHESIS OF TEDUGLUTIDE DNPEP, GCLC, PTMS PPARA 3983/4885PPARG 4024/4885ACE 533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.