Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28072348 | 0.70 | SRC (0.50) | ALDH1A1HPGDPABPC1EIF4HKDM4E | |
| SCHEMBL27368473 | 0.69 | PABPC1 (0.45) | ALDH1A1HPGDPABPC1EIF4HKDM4E | |
| SCHEMBL2936658 | 0.69 | RAB9A (0.45) | ALDH1A1HPGDKDM4EMAPTLMNA | |
| SCHEMBL11548967 | 0.69 | ALDH1A1 (0.47) | ALDH1A1HPGDPABPC1EIF4HKDM4E | |
| SCHEMBL4208219 | 0.67 | KDM4E (0.62) | ALDH1A1HPGDPABPC1EIF4HKDM4E | |
| SCHEMBL1287810 | 0.67 | NCEH1 (0.57) | ALDH1A1HPGDKDM4EMAPTLMNA | |
| SCHEMBL6298233 | 0.67 | NR4A2 (0.61) | ALDH1A1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL9505735 | 0.66 | MAPT (0.58) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL6995149 | 0.66 | SMN1; SMN2 (0.52) | ALDH1A1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL24482887 | 0.66 | ALDH1A1 (0.61) | ALDH1A1HPGDPABPC1EIF4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |