SCHEMBL29407069

SCHEMBL29407069

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ XIAP P98170 1/20 0.52
▸ ENPEP Q07075 5/20 0.45
▸ NPY1R P25929 2/20 0.44
▸ NTSR2 O95665 1/20 0.44
▸ NTSR1 P30989 1/20 0.44
▸ F2 P00734 4/20 0.44
▸ ACE P12821 2/20 0.43
▸ REN P00797 1/20 0.43
▸ GRB2 P62993 1/20 0.42
▸ OPRM1 P35372 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31235878 0.91 NTSR1 (0.48) XIAPNPY1RNTSR2NTSR1F2
SCHEMBL31235876 0.91 NTSR1 (0.48) XIAPNPY1RNTSR2NTSR1F2
SCHEMBL31235886 0.89 XIAP (0.45) XIAPNPY1RNTSR2NTSR1F2
SCHEMBL31235872 0.88 XIAP (0.46) XIAPNPY1RF2OPRM1
SCHEMBL29352327 0.87 XIAP (0.55) XIAPACERENGRB2
SCHEMBL29870992 0.87 XIAP (0.55) XIAPACERENGRB2
SCHEMBL31747054 0.87 XIAP (0.57) XIAPACERENGRB2OPRM1
SCHEMBL30532202 0.86 XIAP (0.53) XIAPENPEPNTSR2NTSR1F2
SCHEMBL29452627 0.85 XIAP (0.50) XIAPNPY1RNTSR2NTSR1GRB2
SCHEMBL31235877 0.85 NPY1R (0.52) NPY1RNTSR2NTSR1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903699-A NIR-II region fluorescent probe for granzyme B detection, and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2023-10-20 — — CN claimed
CN-114107435-A Activatable photoacoustic-fluorescence dual-mode probe for real-time monitoring of immunotherapy and application 广东省人民医院 2022-03-01 — — CN claimed
EP-4733324-A2 METHOD OF PRODUCING A BINDER-TOXIN FUSION PROTEIN IN A PLANT CELL OR A WHOLE PLANT ATB Therapeutics (BE) 2026-04-29 — — EP disclosed
US-20250346648-A1 MAGE A4 T CELL RECEPTORS MEDIGENE IMMUNOTHERAPIES GMBH (DE) 2025-11-13 — — US disclosed
EP-3927831-B1 METHOD OF PRODUCING A BINDER-TOXIN FUSION PROTEIN IN A PLANT CELL OR A WHOLE PLANT ATB THERAPEUTICS (BE) 2025-11-12 — — EP disclosed
EP-4631516-A2 MAGE A4 T CELL RECEPTORS Medigene Immunotherapies GmbH (DE) 2025-10-15 — — EP disclosed
US-12344654-B2 Mage A4 T cell receptors MEDIGENE IMMUNOTHERAPIES GMBH (DE) 2025-07-01 — — US disclosed
EP-3946621-B1 MAGE A4 T CELL RECEPTORS MEDIGENE IMMUNOTHERAPIES GMBH (DE) 2025-05-21 — — EP disclosed
US-20240376517-A1 GRANZYME B DETECTION THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2024-11-14 — — US disclosed
EP-4352076-A1 GRANZYME B DETECTION The University Court Of The University of Edinburgh (GB) 2024-04-17 — — EP disclosed
CN-116903699-A NIR-II region fluorescent probe for granzyme B detection, and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2023-10-20 — — CN disclosed
US-20230203108-A1 IMPROVED GRANZYME B VARIANT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-06-29 — — US disclosed
US-20230159612-A1 MAGE A4 T CELL RECEPTORS REGENERON PHARMACEUTICALS, INC. 2023-05-25 — — US disclosed
CN-115925972-A Method for producing conjugate-toxin fusion proteins in plant cells or whole plants ATB治疗公司 2023-04-07 — — CN disclosed
EP-4159237-A1 IMPROVED GRANZYME B VARIANT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-04-05 — — EP disclosed
WO-2022258997-A1 GRANZYME B DETECTION THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2022-12-15 — — WO disclosed
CN-113728107-B Method for producing conjugate-toxin fusion proteins in plant cells or whole plants ATB治疗公司 2022-06-24 — — CN disclosed
US-20220090113-A1 METHOD OF PRODUCING A BINDER-TOXIN FUSION PROTEIN IN A PLANT CELL OR A WHOLE PLANT ATB THERAPEUTICS (BE) 2022-03-24 — — US disclosed
CN-114107435-A Activatable photoacoustic-fluorescence dual-mode probe for real-time monitoring of immunotherapy and application 广东省人民医院 2022-03-01 — — CN disclosed
CN-114126716-A MAGE A4T cell receptor 基因医疗免疫疗法有限责任公司 2022-03-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220090113-A1 METHOD OF PRODUCING A BINDER-TOXIN FUSION PROTEIN IN A PLANT CELL OR A WHOLE PLANT MAX, PHAX, TIAL1 XIAP 1534/4885ENPEP 955/4885NPY1R 3994/4885
US-20240376517-A1 GRANZYME B DETECTION GZMB, CTSB, DNASE1L3 XIAP 598/4885ENPEP 52/4885NPY1R 1620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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