Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | NPY1R | P25929 | 3/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31235872 | 0.93 | XIAP (0.46) | XIAPF2NPY1RNPY2RNPY4R | |
| SCHEMBL29407069 | 0.89 | XIAP (0.52) | XIAPF2NPY1RNTSR2NTSR1 | |
| SCHEMBL31235878 | 0.89 | NTSR1 (0.48) | XIAPF2NPY1RNPY2RNPY4R | |
| SCHEMBL31235876 | 0.84 | NTSR1 (0.48) | XIAPF2NPY1RNPY2RNPY4R | |
| SCHEMBL30102062 | 0.82 | XIAP (0.43) | XIAPNPY1RCALCRLNPY2RNPY4R | |
| SCHEMBL30577828 | 0.82 | XIAP (0.50) | XIAPACEREN | |
| SCHEMBL29452627 | 0.82 | XIAP (0.50) | XIAPNPY1RCALCRLNPY2RNPY4R | |
| SCHEMBL30532202 | 0.81 | XIAP (0.53) | XIAPF2CALCRLNTSR2NTSR1 | |
| SCHEMBL10773608 | 0.81 | APLNR (0.43) | CALCRLKEAP1 | |
| SCHEMBL10773591 | 0.81 | APLNR (0.43) | CALCRLKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376517-A1 | GRANZYME B DETECTION | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2024-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376517-A1 | GRANZYME B DETECTION | GZMB, CTSB, DNASE1L3 | XIAP 598/4885F2 2290/4885NPY1R 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.