SCHEMBL29408015

SCHEMBL29408015

[N-]=[N+]=Nc1ccc(F)cc1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
MPI P34949 1/20 0.38
HTT P42858 1/20 0.38
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
CA3 P07451 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GRIN2D O15399 2/20 0.32
GRIN3B O60391 2/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14159424 1.00 ALDH1A1 (0.38) ALDH1A1MAPTKDM4ELMNAMPI
SCHEMBL27813956 0.83 KDM4E (0.33) ALDH1A1MAPTKDM4ELMNAMPI
SCHEMBL30280670 0.83 CA3 (0.38) ALDH1A1MAPTLMNACES2CES1
SCHEMBL20263273 0.83 CA3 (0.38) ALDH1A1MAPTLMNACES2CES1
SCHEMBL17382860 0.79 CA3 (0.45) CA3CA6CA5ACA9CA14
SCHEMBL20191938 0.79 TUBB4A (0.35) MAPTLMNATDP1
SCHEMBL15508955 0.79 PKM (0.32)
SCHEMBL22683536 0.79 ESR1 (0.37)
SCHEMBL16845848 0.79 NFE2L2 (0.33) MAPTNFE2L2
SCHEMBL26618043 0.79 DGAT1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998270-A Microbiocidal pyrazole derivatives 先正达农作物保护股份公司 2025-05-13 CN disclosed
CN-119998269-A Microbiocidal pyrazole derivatives 先正达农作物保护股份公司 2025-05-13 CN disclosed
CN-119403559-A Lincomamides and uses thereof 哈佛大学的校长及成员们 2025-02-07 CN disclosed
CN-115850268-A Pyrrolopyrimidines as CFTR potentiators 囊性纤维化基金会 2023-03-28 CN disclosed
CN-110300589-B Bicyclic heteroaryl derivatives as CFTR potentiators 囊性纤维化基金会 2023-03-10 CN disclosed
CN-110337294-B Pyrrolopyrimidines as CFTR potentiators 囊性纤维化基金会 2022-11-01 CN disclosed
CN-114127066-A Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase 爱杜西亚药品有限公司 2022-03-01 CN disclosed