SCHEMBL29414883

SCHEMBL29414883

CC(C)c1cc2c(cc1O)[C@@]1(C)C[C@@H](O)CC(C)(C)[C@@H]1CC2

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KARS1 Q15046 1/20 0.56
▸ CYP19A1 P11511 1/20 0.41
▸ POLA1 P09884 4/20 0.40
▸ NR1I2 O75469 1/20 0.40
▸ OPRK1 P41145 1/20 0.40
▸ FDPS P14324 6/20 0.39
▸ BCL9 O00512 3/20 0.38
▸ CTNNB1 P35222 3/20 0.38
▸ CYP3A4 P08684 3/20 0.38
▸ MAPT P10636 3/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ USP2 O75604 2/20 0.38
▸ TP53 P04637 2/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ PTGES O14684 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29507670 1.00 KARS1 (0.56) KARS1CYP19A1POLA1NR1I2OPRK1
SCHEMBL18290296 0.86 KARS1 (0.52) KARS1POLA1FDPSCYP3A4MAPT
Ferruginol SCHEMBL5315022 0.81 KARS1 (0.73) KARS1CYP19A1POLA1NR1I2OPRK1
Ferruginol SCHEMBL13423521 0.81 KARS1 (0.73) KARS1CYP19A1POLA1NR1I2OPRK1
Ferruginol SCHEMBL155580 0.81 KARS1 (0.73) KARS1CYP19A1POLA1NR1I2OPRK1
Hinokiol SCHEMBL18290363 0.79 KARS1 (0.63) KARS1CYP19A1POLA1NR1I2OPRK1
Hinokiol SCHEMBL854936 0.79 KARS1 (0.63) KARS1CYP19A1POLA1NR1I2OPRK1
Sempervirol SCHEMBL10524412 0.76 KARS1 (0.66) KARS1CYP19A1NR1I2OPRK1FDPS
Sempervirol SCHEMBL10524413 0.76 KARS1 (0.66) KARS1CYP19A1NR1I2OPRK1FDPS
Sempervirol SCHEMBL29495146 0.76 KARS1 (0.66) KARS1CYP19A1NR1I2OPRK1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118121593-B Pharmaceutical composition for preventing and/or treating Alzheimer disease and application thereof 首都医科大学宣武医院 2025-02-14 — — CN claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 — — CN disclosed
US-20260102376-A1 USE OF DIHYDROTANSHINONE I DERIVATIVE IN PREPARATION OF DRUG FOR TREATING CEREBRAL CAVERNOUS MALFORMATION Nanjing University of Chinese Medicine (CN) 2026-04-16 — — US disclosed
CN-120081733-A Compound with anti-tumor effect in Salvia officinalis, separation method and application 华中科技大学 2025-06-03 — — CN disclosed
CN-116687945-B Application of compound in preparing scar reducing agent and scar removing external agent 黑龙江龙德药业有限公司 2025-05-30 — — CN disclosed
CN-119936250-A Construction method of ginseng and motherwort blood-nourishing particle fingerprint and fingerprint thereof 陕西白鹿制药股份有限公司 2025-05-06 — — CN disclosed
US-20250137015-A1 YEAST PLATFORM FOR RENEWABLE INDUSTRIAL TERPENE PRODUCTION Wang, Zhen (US) 2025-05-01 — — US disclosed
CN-119380826-B Chinese patent medicine network pharmacology analysis method and model construction method based on multiscale information entropy 首都医科大学附属北京朝阳医院 2025-04-08 — — CN disclosed
CN-118853691-B Salvia miltiorrhiza gene SmWRKY and application thereof 陕西省西安植物园(陕西省植物研究所) 2025-04-08 — — CN disclosed
CN-119709773-A Application of SmbHLH130,130 gene in improving tanshinone and salvianolic acid content in red sage root 浙江理工大学 2025-03-28 — — CN disclosed
CN-113791154-B Method for identifying chemical components in Xuebijing injection 天津中医药大学 2023-06-23 — — CN disclosed
CN-116183790-A Multi-index component content of ginseng and immortal pulse-raising oral liquid and fingerprint detection method thereof 山东步长制药股份有限公司 2023-05-30 — — CN disclosed
CN-113248514-B Dimethyldeuterated carnosol, preparation method thereof and application thereof in preparation of drugs for treating cachexia 华东师范大学 2023-03-31 — — CN disclosed
CN-115154562-A A topical composition for treating cancer, and its preparation method 何建设 2022-10-11 — — CN disclosed
CN-115058438-A Gene SmDNMT2 for efficiently promoting accumulation of tanshinone and application thereof 浙江理工大学 2022-09-16 — — CN disclosed
US-20220291237-A1 Gene Expression Inflammatory Age and Its Uses Edifice Health, Inc. (US) 2022-09-15 — — US disclosed
CN-114948881-A Octreotide acetate microsphere and preparation method thereof 烟台大学 2022-08-30 — — CN disclosed
CN-114836449-A Gene SmCMT3 for efficiently promoting accumulation of tanshinone and application thereof 浙江理工大学 2022-08-02 — — CN disclosed
CN-114761572-A Cannabinoid concentrates and isolates, methods of obtaining the same, and uses thereof 赫博利生物科技股份公司 2022-07-15 — — CN disclosed
CN-111667889-B Method for predicting content of quality marker in salvia miltiorrhiza 山东中医药大学 2022-03-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102376-A1 USE OF DIHYDROTANSHINONE I DERIVATIVE IN PREPARATION OF DRUG FOR TREATING CEREBRAL CAVERNOUS MALFORMATION CACNA1A, SDHA, MVD KARS1 1970/4885CYP19A1 687/4885POLA1 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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