Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19085489 | 0.88 | FPR2 (0.45) | FPR2TGM2ABCB1USP2MEN1 | |
| SCHEMBL19494774 | 0.85 | USP2 (0.53) | FPR2TGM2ABCB1USP2MEN1 | |
| SCHEMBL12763951 | 0.85 | POLB (0.50) | FPR2TGM2ABCB1USP2MEN1 | |
| SCHEMBL17109310 | 0.85 | ABCB1 (0.44) | FPR2TGM2ABCB1USP2MEN1 | |
| Hydrochloric Acid SCHEMBL18617 | 0.83 | MEN1 (0.60) | FPR2TGM2USP2MEN1BLM | |
| Hydrochloric Acid SCHEMBL30207638 | 0.83 | MEN1 (0.60) | FPR2TGM2USP2MEN1BLM | |
| Hydrochloric Acid SCHEMBL29354092 | 0.83 | MEN1 (0.60) | FPR2TGM2USP2MEN1BLM | |
| SCHEMBL19494880 | 0.83 | ABCB1 (0.45) | FPR2TGM2ABCB1USP2MEN1 | |
| SCHEMBL6056220 | 0.83 | ABCB1 (0.43) | ABCB1USP2MEN1BLMKMT2A | |
| SCHEMBL12056738 | 0.83 | ABCB1 (0.43) | ABCB1USP2MEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119156399-A | Fully human monoclonal antibodies against human granulin precursors | A&G 药品公司 | 2024-12-17 | — | — | CN | claimed |
| US-11691025-B2 | Methods and compositions for reversing or mitigating skin aging | KLOX TECHNOLOGIES INC. (CA) | 2023-07-04 | — | — | US | claimed |
| CN-114454524-A | Preparation method of high-definition blue-light-proof, ultraviolet-proof and near-infrared-proof PC lens and PC lens | 苏州讯能光电科技有限公司 | 2022-05-10 | — | — | CN | claimed |
| US-20220111050-A1 | BIOPHOTONIC COMPOSITIONS, METHODS, AND KITS FOR INHIBITING AND DISRUPTING BIOFILMS | FLE INTERNATIONAL S.R.L. (IT) | 2022-04-14 | — | — | US | claimed |
| EP-4424785-B1 | WRITING INSTRUMENT | MITSUBISHI PENCIL CO (JP) | 2025-11-12 | — | — | EP | disclosed |
| US-12421452-B2 | Method for producing liquid-crystal polyester processed product | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2025-09-23 | — | — | US | disclosed |
| US-20250268474-A1 | Systems and Methods for Detecting Fibrosis | 3HELIX, INC. (US) | 2025-08-28 | — | — | US | disclosed |
| EP-4599073-A2 | METHODS FOR ACTIVELY LOADING THERAPEUTIC MOLECULES INTO MODIFIED EXTRACELLULAR VESICLES FOR TARGETED DELIVERY TO CELLS | Mercury Bio, Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| EP-3865137-B1 | COMPOSITIONS AND THEIR USE IN THE TREATEMENT OR PREVENTION OF VENOUS INSUFFICIENCY | ITALFARMACO SPA (IT) | 2025-06-25 | — | — | EP | disclosed |
| US-20250195621-A1 | SYNTHETIC PLATELETS | UNIV CASE WESTERN RESERVE (US) | 2025-06-19 | — | — | US | disclosed |
| WO-2025075673-A1 | LIGHT-ACTIVATED LOADING OF THERAPEUTIC MOLECULES INTO MODIFIED EXTRACELLULAR VESICLES FOR TARGETED DELIVERY TO CELLS | MERCURY BIO, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2025064908-A1 | DIFFERENTIAL ACOUSTIC IMPEDANCE PARTICLES FOR ULTRASONIC DRUG UNCAGING | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-03-27 | — | — | WO | disclosed |
| WO-2022115137-A1 | FLUORESCENT MICROSPHERES EVENLY COATED WITH MAGNETIC PARTICLES AND METHODS OF USE | EMISSION INC. (US) | 2022-06-02 | — | — | WO | disclosed |
| CN-109423064-B | Azo pigment, colorant for color filter, coloring composition for color filter, and color filter | 东洋油墨SC控股株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-114454524-A | Preparation method of high-definition blue-light-proof, ultraviolet-proof and near-infrared-proof PC lens and PC lens | 苏州讯能光电科技有限公司 | 2022-05-10 | — | — | CN | disclosed |
| WO-2022093940-A1 | TRANSCRIPTOMICS WITH ELECTROPHYSIOLOGICAL RECORDING | THE BROAD INSTITUTE, INC. (US) | 2022-05-05 | — | — | WO | disclosed |
| US-20220111050-A1 | BIOPHOTONIC COMPOSITIONS, METHODS, AND KITS FOR INHIBITING AND DISRUPTING BIOFILMS | FLE INTERNATIONAL S.R.L. (IT) | 2022-04-14 | — | — | US | disclosed |
| US-11291685-B2 | Polymer nanoparticle, polymer composition, method of making a polymer nanoparticle, method for treatment of bacterial biofilms, and method for detection of bacterial biofilms | THE UNIVERSITY OF MASSACHUSETTS (US) | 2022-04-05 | — | — | US | disclosed |
| WO-2022064011-A1 | IMMUNOTHERAPY | THE FRANCIS CRICK INSTITUTE LIMITED (GB) | 2022-03-31 | — | — | WO | disclosed |
| CN-107015436-B | Colored curable resin composition, color filter, and display device comprising the color filter | 住友化学株式会社 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11291685-B2 | Polymer nanoparticle, polymer composition, method of making a polymer nanoparticle, method for treatment of bacterial biofilms, and method for detection of bacterial biofilms | RPN1, COL1A1, PFN1 | FPR2 892/4885TGM2 3266/4885ABCB1 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.