SCHEMBL29429570

SCHEMBL29429570

CC(C)C[C@H](NC(=O)[C@H](N)Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 8/20 0.60
▸ OPRM1 P35372 7/20 0.60
▸ SLC6A2 P23975 2/20 0.58
▸ CALCRL Q16602 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30788019 0.86 SLC6A2 (0.68) OPRD1OPRM1SLC6A2CALCRL
SCHEMBL31596917 0.86 SLC6A2 (0.71) OPRD1OPRM1SLC6A2CALCRL
SCHEMBL29398783 0.85 OPRM1 (0.57) OPRD1OPRM1SLC6A2CALCRL
SCHEMBL30788025 0.85 CALCRL (0.61) SLC6A2CALCRL
SCHEMBL30439765 0.83 SLC6A2 (0.56) OPRD1OPRM1SLC6A2CALCRL
SCHEMBL31720929 0.83 SLC6A2 (0.56) OPRD1OPRM1SLC6A2CALCRL
SCHEMBL30289679 0.83 SLC6A2 (0.58) OPRD1OPRM1SLC6A2CALCRL
SCHEMBL30407795 0.83 NMUR2 (0.54) OPRD1OPRM1
SCHEMBL30788014 0.82 CALCRL (0.60) SLC6A2CALCRL
SCHEMBL30102155 0.82 OPRD1 (0.55) OPRD1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230406911-A1 COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2023-12-21 — — US claimed
EP-4237445-A2 COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM Research Institute at Nationwide Children's Hospital (US) 2023-09-06 — — EP claimed
CN-116490778-A Compositions and methods for preventing, inhibiting, disrupting or treating a multi-microbial biofilm 国家儿童医院研究所 2023-07-25 — — CN claimed
CN-114796444-A Active composition for relieving chronic alcoholic liver injury and preparation method and application thereof 上海朗泰凯尔生物技术有限公司 2022-07-29 — — CN claimed
WO-2022094433-A2 COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2022-05-05 — — WO claimed
US-12595288-B2 Vasopressin-2 receptor antagonist peptides and uses thereof COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2026-04-07 — — US disclosed
US-12577291-B2 Means and methods for treating and diagnosing fibrosis or fibrosis-associated diseases DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2026-03-17 — — US disclosed
US-12410229-B2 PTH mimetic peptide based on protein domain reconstruction and application thereof YANG DEHONG (CN) 2025-09-09 — — US disclosed
US-20250258166-A1 MEANS AND METHODS FOR HIGH-THROUGHPUT GLYCOPROFILING OF PROTEINS GLYCANOSTICS S.R.O. (SK) 2025-08-14 — — US disclosed
EP-2742058-B1 ANTI-IL-6 VACCINE COMPOSITION PEPTINOV (FR) 2025-07-23 — — EP disclosed
WO-2025096668-A1 SYSTEM AND COMPOSITIONS COMPRISING MHC SCAFFOLD AND METHODS OF IDENTIFYING ANTIGENS USING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-05-08 — — WO disclosed
CN-119930842-A Means and methods for treating angiogenesis, fibrosis and cancer related diseases with protein oligomers comprising NC-1-Fc 海德堡生物技术有限公司 2025-05-06 — — CN disclosed
EP-4096697-A1 PEPTIDES USEFUL IN PRESERVATION AND/OR RESTORATION OF FUNCTIONAL PANCREATIC ISLETS AND IN TREATING DIABETES The National Institute for Biotechnology in the Negev Ltd. (IL) 2022-12-07 — — EP disclosed
WO-2022248615-A2 HEXOKINASE-DERIVED PEPTIDES AND THERAPEUTICAL USES THEREOF INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-12-01 — — WO disclosed
CN-111825760-B Polypeptide and application thereof in resisting glomerular basement membrane disease 北京大学第一医院 2022-11-11 — — CN disclosed
CN-114796444-A Active composition for relieving chronic alcoholic liver injury and preparation method and application thereof 上海朗泰凯尔生物技术有限公司 2022-07-29 — — CN disclosed
WO-2022094433-A2 COMPOSITIONS AND METHODS FOR PREVENTING, INHIBITING, DISRUPTING, OR TREATING A POLYMICROBIAL BIOFILM RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2022-05-05 — — WO disclosed
WO-2022087519-A1 SURFACE MODIFIED SCAFFOLDS AND METHODS OF USE THEREOF BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2022-04-28 — — WO disclosed
CN-108350046-B Analogs of VDAC 1-derived peptides 在本-古里安大学的B.G.内盖夫科技与应用有限公司 2022-04-01 — — CN disclosed
US-20220054584-A1 ANTIMICROBIAL FUSION PEPTIDES THE LUNDQUIST INST FOR BIOMEDICAL INNOVATION AT HARBOR UCLA MEDICAL CENTER (US) 2022-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595288-B2 Vasopressin-2 receptor antagonist peptides and uses thereof AVPR2, AVPR1A, AVPR1B OPRD1 160/4885OPRM1 206/4885SLC6A2 292/4885
US-12577291-B2 Means and methods for treating and diagnosing fibrosis or fibrosis-associated diseases MMP1, FN1, COL14A1 OPRD1 4047/4885OPRM1 3787/4885SLC6A2 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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