Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22206250 | 0.92 | KDM4E (0.37) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| Pyromellitic Acid SCHEMBL22463123 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL22206255 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| Pyromellitic Acid SCHEMBL9693112 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| Pyromellitic Acid SCHEMBL1881547 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| Pyromellitic Acid SCHEMBL7732128 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| Pyromellitic Acid SCHEMBL1150971 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| Pyromellitic Acid SCHEMBL10454935 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| Pyromellitic Acid SCHEMBL22463129 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| Pyromellitic Acid SCHEMBL6263960 | 0.69 | KDM4E (0.48) | KDM4EALDH1A1HPGDPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122025666-A | Multi-scale gradient coupling proton exchange membrane fuel cell catalytic layer water retaining structure and preparation method thereof | 常州氢龙科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| WO-2026090101-A2 | ELECTROCHEMICAL CAPACITIVE BIOFOULING RESISTANT BIOSENSORS AND METHODS OF MAKING AND USING SAME | WASHINGTON UNIVERSITY (US) | 2026-04-30 | — | — | WO | claimed |
| EP-4721855-A1 | POLYMERIC FIBER COMPOSITES COMPRISING METAL-ORGANIC FRAMEWORKS AND USE THEREOF | Techzero Buildings, S.A. (PT) | 2026-04-08 | — | — | EP | claimed |
| US-20260091339-A1 | POLYMERYC FIBER COMPOSITES COMPRISING METAL-ORGANIC FRAMEWORKS AND USE THEREOF | TECHZERO BUILDINGS S A (PT) | 2026-04-02 | — | — | US | claimed |
| CN-120054538-A | NiCo-S/NiCo-OH-CL dual-function catalyst with heterostructure and preparation method thereof | 湖北大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119900052-A | Electrocatalytic material of MOF (metal oxide fiber) encapsulated polyoxometallate for glycerol oxidation and preparation method thereof | 上海理工大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119725440-A | MOF-derived bimetallic selenide embedded nitrogen-doped carbon composite material and preparation method and application thereof | 合肥工业大学 | 2025-03-28 | — | — | CN | claimed |
| CN-116040607-B | Porous carbon hybrid material with double-layer hollow core-shell structure, and preparation method and application thereof | 合肥工业大学 | 2025-03-07 | — | — | CN | claimed |
| CN-119219937-A | Preparation method and application of MOF-74 with hollow structure | 中国科学院上海应用物理研究所 | 2024-12-31 | — | — | CN | claimed |
| CN-119140113-A | Three-dimensional core-shell hydrangea MnOX@Co3O4Preparation method and application of catalyst | 嘉应学院 | 2024-12-17 | — | — | CN | claimed |
| CN-114522688-A | Porous carbon loaded bimetallic catalyst and preparation and application thereof | 中国科学院大连化学物理研究所 | 2022-05-24 | — | — | CN | claimed |
| CN-113061264-B | Chiral MOFs material and application thereof as chromatographic stationary phase in chiral drug resolution | 郑州大学 | 2022-05-17 | — | — | CN | claimed |
| CN-114478167-A | Method and system for recovering refinery dry gas by using metal organic framework material | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114497828-A | Fusiform Ag/Co3O4Composite material, preparation method thereof and application thereof in lithium air battery | 合肥国轩高科动力能源有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114478173-A | Method, system and application for recovering refinery dry gas | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-113174143-B | Metal organic framework/multilayer carbon composite wave-absorbing material and preparation method thereof | 鲁东大学 | 2022-05-10 | — | — | CN | claimed |
| CN-114452842-A | CNC/Cu-MOF-74 composite material surface modified PVDF membrane, and preparation method and application thereof | 上海电力大学 | 2022-05-10 | — | — | CN | claimed |
| CN-110161100-B | Preparation method of label-free electrochemical sensor for cardiac troponin I and detection method for cTnI | 闽南师范大学 | 2022-04-08 | — | — | CN | claimed |
| CN-114225910-A | Aminated modified Co-MOFs material with NO adsorption separation performance | 桂林理工大学 | 2022-03-25 | — | — | CN | claimed |
| CN-114133582-A | Preparation of three-dimensional structure Co-MOF-74 material and application of VOCs (volatile organic Compounds) of material | 桂林理工大学 | 2022-03-04 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260091339-A1 | POLYMERYC FIBER COMPOSITES COMPRISING METAL-ORGANIC FRAMEWORKS AND USE THEREOF | PUF60, MT-CO2, MIF | KDM4E 2111/4885ALDH1A1 1444/4885HPGD 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.