Neurokinin B

Neurokinin B

SCHEMBL29440672

CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(=O)O)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(CCSC)NC(=O)C(N)CC(=O)O)C(C)C)C(N)=O

nearest known ligand 0.66

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Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GRPR P30550 15/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Neurokinin B SCHEMBL29390479 1.00 GRPR (0.59) GRPR
SCHEMBL30350156 0.94 TACR3 (0.57) GRPR
SCHEMBL29406603 0.90 CTSB (0.54) —
Neurokinin A SCHEMBL29374005 0.88 PTH1R (0.62) —
Neurokinin A SCHEMBL29374084 0.88 PTH1R (0.62) —
Neurokinin B SCHEMBL29372314 0.88 GRPR (0.53) GRPR
SCHEMBL29569383 0.87 OPRM1 (0.57) GRPR
SCHEMBL29678561 0.86 CCKAR (0.51) —
SCHEMBL29678344 0.84 NPY4R (0.56) —
SCHEMBL14364816 0.84 GRPR (0.58) GRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695385-A1 GENE EDITING FOR INTERVERTEBRAL, INTRA- AND PERIDISCAL THERAPY AND ASSOCIATED SPINAL DISORDERS Orthobio Therapeutics, Inc. (US) 2026-02-18 — — EP disclosed
EP-4694913-A2 LIPID NANOPARTICLES FOR GENE EDITING SYSTEMS Orthobio Therapeutics, Inc. (US) 2026-02-18 — — EP disclosed
US-20260028588-A1 DIFFERENTIATION OF STEM CELLS IN SUSPENSION CULTURE UMOJA BIOPHARMA, INC. (US) 2026-01-29 — — US disclosed
US-12534511-B2 Serum albumin-binding fibronectin type III domains BRISTOL-MYERS SQUIBB COMPANY (US) 2026-01-27 — — US disclosed
EP-4180799-B1 METHOD OF CLASSIFYING MILK PPB TECH PTY LTD (AU) 2025-12-24 — — EP disclosed
US-20250382586-A1 MANUFACTURING VIRAL PARTICLES UMOJA BIOPHARMA, INC. (US) 2025-12-18 — — US disclosed
US-20250367290-A1 ENGINEERED STEM CELLS AND USES THEREOF Umoja Bioharma, Inc. (US) 2025-12-04 — — US disclosed
US-20250360149-A1 GPCR INHIBITORS AND USES THEREOF GPCR THERAPEUTICS INC (KR) 2025-11-27 — — US disclosed
US-20250354118-A1 COMPOSITIONS AND METHODS FOR NK CELL DIFFERENTIATION UMOJA BIOPHARMA, INC. (US) 2025-11-20 — — US disclosed
WO-2025235604-A1 FUSION PROTEIN FOR USE AS IMMUNE CELL ENGAGER UMOJA BIOPHARMA, INC. (US) 2025-11-13 — — WO disclosed
US-20230145413-A1 FAST-OFF RATE SERUM ALBUMIN BINDING FIBRONECTIN TYPE III DOMAINS BRISTOL-MYERS SQUIBB COMPANY 2023-05-11 — — US disclosed
US-11610650-B2 Method and system for designing polynucleotide sequences and polynucleotide sequences obtained thereby RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-03-21 — — US disclosed
US-20220314221-A1 MICROFLUIDIC DEVICE FOR ANALYZING GENE EXPRESSION YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-10-06 — — US disclosed
US-11434275-B2 Fast-off rate serum albumin binding fibronectin type III domains BRISTOL-MYERS SQUIBB COMPANY (US) 2022-09-06 — — US disclosed
US-11396012-B2 Microfluidic device for analyzing gene expression YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-07-26 — — US disclosed
US-11385234-B2 Methods and systems for detecting an analyte or classifying a sample COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2022-07-12 — — US disclosed
US-20220204589-A1 SERUM ALBUMIN-BINDING FIBRONECTIN TYPE III DOMAINS BRISTOL-MYERS SQUIBB COMPANY 2022-06-30 — — US disclosed
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2022-05-05 — — US disclosed
EP-3572424-B1 SERUM ALBUMIN-BINDING FIBRONECTIN TYPE III DOMAINS BRISTOL MYERS SQUIBB CO (US) 2022-04-20 — — EP disclosed
EP-3395372-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM ENHANX BIOPHARM INC (TW) 2022-04-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367290-A1 ENGINEERED STEM CELLS AND USES THEREOF IL2RA, IL2, IL15RA GRPR 385/4885
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG GRPR 936/4885
US-12534511-B2 Serum albumin-binding fibronectin type III domains FN1, ALB, FGB GRPR 4759/4885
US-20260028588-A1 DIFFERENTIATION OF STEM CELLS IN SUSPENSION CULTURE BMP4, FLT4, FGF2 GRPR 3215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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