Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE12 | Q6L8Q7 | 2/20 | 1.00 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | FASN | P49327 | 11/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30357429 | 0.69 | PDE12 (1.00) | PDE12KDM1AFASN | |
| SCHEMBL29446570 | 0.59 | PDE12 (0.41) | PDE12 | |
| SCHEMBL4808301 | 0.54 | PGR (0.39) | PDE12KDM1ANR3C1PGRNR3C2 | |
| SCHEMBL17883794 | 0.53 | CYP11B2 (0.40) | PDE12 | |
| SCHEMBL4812180 | 0.52 | CYP11B1 (0.41) | KDM1ANR3C1PGRNR3C2AR | |
| SCHEMBL17896616 | 0.52 | CYP11B2 (0.43) | — | |
| SCHEMBL4813751 | 0.52 | PLA2G4A (0.46) | KDM1ANR3C1PGRNR3C2AR | |
| SCHEMBL17896612 | 0.51 | CYP11B2 (0.52) | — | |
| SCHEMBL31347092 | 0.51 | DAPK3 (0.44) | — | |
| SCHEMBL10175104 | 0.51 | CYP11B2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213354-A | Preparation method of trans-2- (substituted phenyl) -3-hydroxymethyl morpholine | 上海皓元生物医药科技有限公司 | 2022-03-22 | — | — | CN | disclosed |