SCHEMBL2944739

SCHEMBL2944739

CO[Si](CCCc1cccc(CCl)c1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.42
MTNR1B P49286 2/20 0.42
CHRM2 P08172 2/20 0.40
CHRM1 P11229 2/20 0.40
CHRM3 P20309 2/20 0.40
TSHR P16473 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
TTR P02766 1/20 0.36
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15209652 0.91 CHRM2 (0.45) MTNR1AMTNR1BCHRM2CHRM1CHRM3
SCHEMBL926607 0.90 TSHR (0.40) MTNR1AMTNR1BCHRM2CHRM1CHRM3
SCHEMBL2946293 0.84 MTNR1A (0.36) MTNR1AMTNR1BCYP4F2CYP4A11
SCHEMBL2955473 0.83 CHRM2 (0.40) MTNR1AMTNR1BCHRM2CHRM1CHRM3
SCHEMBL2950991 0.82 CALM1 (0.39) MTNR1AMTNR1BTAAR1TTR
SCHEMBL2951759 0.81 LPL (0.35) MTNR1AMTNR1B
SCHEMBL2945688 0.80 LPL (0.37)
SCHEMBL10988339 0.80 MAOA (0.50) MTNR1AMTNR1BCHRM2CHRM1CHRM3
SCHEMBL15736455 0.80 TAAR1 (0.49) TAAR1
SCHEMBL16669307 0.80 GABRA1 (0.55) MTNR1AMTNR1BCHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7759406-B2 Process for producing polysilsesquioxane graft polymer, pressure-sensitive adhesive, and pressure-sensitive adhesive sheet LINTEC CORPORATION (JP) 2010-07-20 US disclosed
US-20080051487-A1 Process for Producing Polysilsesquioxane Graft Polymer, Pressure-Sensitive Adhesive, and Pressure-Sensitive Adhesive Sheet LINTEC CORPORATION (JP) 2008-02-28 US disclosed