Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617961 | 0.73 | — | — | |
| SCHEMBL10548811 | 0.69 | — | — | |
| SCHEMBL3390306 | 0.67 | — | — | |
| SCHEMBL1101969 | 0.65 | ALDH1A1 (0.33) | TSHR | |
| SCHEMBL23850763 | 0.65 | — | — | |
| SCHEMBL126833 | 0.63 | TSHR (0.40) | TSHR | |
| SCHEMBL13800448 | 0.63 | TSHR (0.40) | TSHR | |
| SCHEMBL25131198 | 0.61 | GABRP (0.31) | — | |
| SCHEMBL28678933 | 0.59 | TSHR (0.36) | TSHR | |
| SCHEMBL4332885 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603597-B1 | OXYCODONE CONJUGATES WITH LOWER ABUSE POTENTIAL AND EXTENDED DURATION OF ACTION | CONTROLLED CHEMICALS INC (US) | 2010-01-06 | — | — | EP | disclosed |
| US-20070203165-A1 | COMPOUNDS AND METHODS FOR LOWERING THE ABUSE POTENTIAL AND EXTENDING THE DURATION OF ACTION OF A DRUG | CONTROLLED CHEMICALS, INC. (US) | 2007-08-30 | — | — | US | disclosed |
| US-7230005-B2 | Compounds and methods for lowering the abuse potential and extending the duration of action of a drug | CONTROLLED CHEMICALS, INC. (US) | 2007-06-12 | — | — | US | disclosed |
| EP-1782834-A2 | OXYCODONE CONJUGATES WITH LOWER ABUSE POTENTIAL AND EXTENDED DURATION OF ACTION | Controlled Chemicals, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| EP-1603597-A2 | OXYCODONE CONJUGATES WITH LOWER ABUSE POTENTIAL AND EXTENDED DURATION OF ACTION | Controlled Chemicals, Inc. (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20040204434-A1 | Compounds and methods for lowering the abuse potential and extending the duration of action of a drug | CONTROLLED CHEMICALS INC. | 2004-10-14 | — | — | US | disclosed |
| WO-2004082620-A2 | OXYCODONE CONJUGATES WITH LOWER THE ABUSE POTENTIAL AND EXTENDED DURATION OF ACTION | CONTROLLED CHEMICALS, INC. (US) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204434-A1 | Compounds and methods for lowering the abuse potential and extending the duration of action of a drug | CRH, OPRK1, SI | TSHR 4533/4885 |
| US-20070203165-A1 | COMPOUNDS AND METHODS FOR LOWERING THE ABUSE POTENTIAL AND EXTENDING THE DURATION OF ACTION OF A DRUG | CRH, OPRK1, SI | TSHR 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.