Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3014039 | 0.80 | NOTUM (0.33) | NOTUMGRM5 | |
| SCHEMBL2945346 | 0.78 | GRM5 (0.32) | NOTUMGRM5 | |
| SCHEMBL7823338 | 0.76 | NOTUM (0.40) | NOTUMGRM5 | |
| SCHEMBL7814733 | 0.76 | ALDH1A1 (0.41) | NOTUMGRM5 | |
| SCHEMBL1843567 | 0.75 | ALDH1A1 (0.43) | NOTUMGRM5 | |
| SCHEMBL3586944 | 0.73 | ALDH1A1 (0.33) | NOTUM | |
| SCHEMBL3573592 | 0.73 | NOTUM (0.38) | NOTUMGRM2GRM5 | |
| SCHEMBL3260136 | 0.72 | SIGMAR1 (0.42) | NOTUM | |
| SCHEMBL3580768 | 0.71 | ALDH1A1 (0.31) | NOTUM | |
| SCHEMBL3580161 | 0.71 | OPRM1 (0.31) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |