Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945346 | 0.93 | GRM5 (0.32) | NOTUMGRM5USP30QPCTALDH1A1 | |
| SCHEMBL6760968 | 0.80 | NOTUM (0.34) | NOTUMGRM5 | |
| SCHEMBL7814733 | 0.77 | ALDH1A1 (0.41) | NOTUMGRM5QPCTKDM4EALDH1A1 | |
| SCHEMBL7823338 | 0.77 | NOTUM (0.40) | NOTUMGRM5QPCTALDH1A1 | |
| SCHEMBL1843567 | 0.76 | ALDH1A1 (0.43) | NOTUMGRM5QPCTKDM4EALDH1A1 | |
| SCHEMBL3573592 | 0.74 | NOTUM (0.38) | NOTUMGRM5QPCTALDH1A1HSD11B1 | |
| SCHEMBL3586944 | 0.74 | ALDH1A1 (0.33) | NOTUMQPCTALDH1A1HSD11B1 | |
| SCHEMBL28296440 | 0.73 | NOTUM (0.33) | NOTUMQPCT | |
| SCHEMBL3260136 | 0.73 | SIGMAR1 (0.42) | NOTUMQPCTALDH1A1 | |
| SCHEMBL3580768 | 0.71 | ALDH1A1 (0.31) | NOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102112471-A | 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | FERRER INT | 2011-06-29 | — | — | CN | disclosed |
| EP-2141161-A1 | 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2010-01-06 | — | — | EP | disclosed |