SCHEMBL29454348

SCHEMBL29454348

CC1=CC[C@@H](C(C)(C)OC(=O)/C=C/c2ccccc2)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
CYP3A4 P08684 2/20 0.46
ALOX15 P16050 2/20 0.46
PTPN1 P18031 1/20 0.41
GLA P06280 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
CHRNA7 P36544 1/20 0.41
STAT3 P40763 1/20 0.41
NR1H4 Q96RI1 2/20 0.40
CYP2C19 P33261 1/20 0.39
EGFR P00533 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1629428 1.00 LMNA (0.46) LMNACYP3A4ALOX15PTPN1GLA
SCHEMBL1629427 1.00 LMNA (0.46) LMNACYP3A4ALOX15PTPN1GLA
SCHEMBL22293372 0.87 LMNA (0.47) LMNACYP3A4ALOX15TDP1KMT2A
SCHEMBL22373120 0.80 NR1H4 (0.43) LMNAGLATDP1KMT2AMEN1
SCHEMBL5604543 0.80 CES2 (0.51) LMNACYP3A4ALOX15PTPN1TDP1
SCHEMBL15470541 0.79 LMNA (0.51) LMNACYP3A4ALOX15PTPN1KMT2A
SCHEMBL25380943 0.79 LMNA (0.57) LMNACYP3A4ALOX15PTPN1TDP1
SCHEMBL25380939 0.77 LMNA (0.59) LMNACYP3A4ALOX15PTPN1TDP1
Acetic Acid SCHEMBL1234733 0.76 LMNA (0.57) LMNACYP3A4ALOX15PTPN1TDP1
SCHEMBL19919389 0.76 LMNA (0.54) LMNACYP3A4ALOX15PTPN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110300575-B Extract of celastrus orbiculatus rattan, cosmetic composition comprising same and cosmetic use thereof ISP投资有限公司 2022-11-15 CN claimed
US-11400389-B2 Marsdenia cundurango creeper extracts, cosmetic compositions comprising them and cosmetic uses of same ISP INVESTMENTS LLC (US) 2022-08-02 US claimed
EP-3579929-B1 MARSDENIA CUNDURANGO ISP INVESTMENTS LLC (US) 2022-04-13 EP claimed
US-20250302014-A1 WASP PEST MANAGEMENT SYSTEM TONER DARADH (IE) 2025-10-02 US disclosed
EP-4518647-A1 WASP PEST MANAGEMENT SYSTEM Toner, Daradh (IE) 2025-03-12 EP disclosed
CN-119184087-A Application of cinnamic acid terpene ester derivatives in prevention and treatment of bacterial wilt 南京中医药大学翰林学院 2024-12-27 CN disclosed
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
WO-2023214095-A1 WASP PEST MANAGEMENT SYSTEM TONER DARADH (IE) 2023-11-09 WO disclosed
EP-3416729-B1 PRO-FRAGRANCE COMPOSITION AQDOT LTD (GB) 2023-09-20 EP disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
CN-110300575-B Extract of celastrus orbiculatus rattan, cosmetic composition comprising same and cosmetic use thereof ISP投资有限公司 2022-11-15 CN disclosed
CN-110300575-B Extract of celastrus orbiculatus rattan, cosmetic composition comprising same and cosmetic use thereof ISP投资有限公司 2022-11-15 CN disclosed
US-11400389-B2 Marsdenia cundurango creeper extracts, cosmetic compositions comprising them and cosmetic uses of same ISP INVESTMENTS LLC (US) 2022-08-02 US disclosed
US-11400389-B2 Marsdenia cundurango creeper extracts, cosmetic compositions comprising them and cosmetic uses of same ISP INVESTMENTS LLC (US) 2022-08-02 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
CN-108601958-B Pro-fragrance compositions 爱客多有限公司 2022-06-17 CN disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 LMNA 4834/4885CYP3A4 4332/4885ALOX15 3088/4885
US-11400389-B2 Marsdenia cundurango creeper extracts, cosmetic compositions comprising them and cosmetic uses of same CUTA, TYR, TPSD1 LMNA 829/4885CYP3A4 925/4885ALOX15 580/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 LMNA 4834/4885CYP3A4 4332/4885ALOX15 3088/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 LMNA 4834/4885CYP3A4 4332/4885ALOX15 3088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.